2025 AIChE Annual Meeting

Session: Biomolecular Engineering: Extracellular Vesicles, Exosomes, and Bio-Sensing Interfaces

This session explores the diagnostic and therapeutic potential of extracellular vesicles, exosomes, and engineered biosensing platforms. Presentations will cover innovations in molecular targeting, cellular communication, and point-of-care detection strategies.

Chair

Jessica Larsen, Clemson University

Co-Chair

Xilal Rima, The Ohio State University

Presentations

08:00 AM

(653a) Hyperspectral Reporters for Long-Distance and Wide-Area Detection of Gene Expression in Metabolically Engineered Bacteria
Yonatan Chemla, Itai Levin, Christopher A. Voigt, Connor Coley

08:18 AM

(653b) Design and Engineering of PpL1 for Sensitive Detection of Antigens in Lateral-Flow Immunoassays Using Rabbit Single-Chain Fv Antibodies
Yoichi Kumada, Yodai Yamamoto, Ngoc Minh Nguyen, Jun-ichi Horiuchi

08:36 AM

(653c) Design of Peptide Affinity Ligands for Tetraspanins for Exosome-Based Early Cancer Detection
Arpan Tapdiya, Young Kwan Cho, Hakho Lee, Carol Hall

08:54 AM

(653d) Microfluidics Model Revealed Sickle Red Blood Cell?Derived Extracellular Vesicles Activate Complement System and Enhance Monocyte Adhesion on Endothelium
Qingrong He, Ran An

09:12 AM

(653e) Modulating Cellular Response through Biophysical Properties of Bacterial Extracellular Vesicles
Rajan Jayasankar, Darby Steinman, Hannah Zierden

09:30 AM

(653f) Genetically Engineered Extracellular Vesicles with Chimeric Antigen Receptor of Human Stem Cell-Derived Neutrophils for Treating Glioblastoma
Colin Esmonde, Li Sun, Yun Chang, Xiaoping Bao, Yan Li

09:48 AM

(653g) Invited Talk: Designing Recombinant Protein Vesicles for Artificial Antigen Presentation
Yeongseon Jang