2021 Synthetic Biology: Engineering, Evolution & Design (SEED)

Session: Poster Presenters - Accepted

Presentations

Development of an In Vivo Method in Nepeta Cataria (catnip) to Characterize the Biosynthetic Pathway behind Nepetalactone Stereoisomer Production
Lira Palmer, Kotaro Yamamoto, Sarah O'Connor, Prashanst Sonawane, Ling Chuang, Marlen Siegmund
Engineering Alternative Degradation Tags for Synthetic Circuits
Prajakta Jadhav, Nicholas C. Butzin
Rapid Generation of Potent Antibodies By Autonomous Hypermutation in Yeast
Alon Wellner
Machine Learning Guided Approach to Bacteriocin Engineering
Jack Kay
Engineering a Global Regulatory System Potentiates Rapid Growth of Saccharomyces Cerevisiae on Numerous Non-Native Substrates
Sean F. Sullivan, Vikas Trivedi, Venkatesh Endalur Gopinarayan
Engineering Endosymbionts Capable of Controlling Mammalian Cell Gene Expression
Cody S. Madsen, Ashley V. Makela, Jonathan W. Hardy, Christopher H. Contag
Exploiting Microbial Cell Factories for the Development and Manufacturing of Novel Biologics and Industrial Products
Rita Cruz
Rapid Synthetic Viral Vectorology for Future Pandemic Response
F. Curtis Hewitt, Anthony D. Kappell, Amanda N. Scholes, Nicolette C. Keplinger
Sibr-Cas Enables Host-Independent and Universal CRISPR Genome Engineering in Prokaryotes
John van der Oost, Constantinos Patinios, Raymond Staals, Colin Ingham, Adini Arifah, Belen Perez, Sjoerd Creutzburg, Servé Kengen
Using Synthetic Biology for Determining Biological Controls on Marine Carbon Sequestration
Swetha Sridhar, Caroline Ajo-Franklin, Johnathan J. Silberg, Caroline A. Masiello
Outline of DNA Construction Process Quality in Performance Indicator Dashboard
John Meng, Miranda Harmon-Smith, Angela Tarver, Robert Evans, Nathan J Hillson, Ian K. Blaby, Jan-Fang Cheng
A New Form of Bio-Active Materials: Blending Dry Cell-Free Systems and Synthetic Polymers
Marilyn S. Lee, Matthew Lux, Maneesh Gupta, Danielle Kuhn, Rebecca Raig, Gregory W. Peterson, John Biondo
Establishing Continuous in Vitro DNA Replication in a Cell-Free System
Laura Grasemann, Sebastian J. Maerkl
An Algorithmic Approach to Program Probiotic Bacterial Strains for In Vivo Diagnostics
Matthew Lebovich, Lauren B. Andrews
the Promoter Calculator - a Sequence-to-Function Biophysical Model of Transcriptional Initiation for Sigma70 Promoters with Any Sequence
Travis La Fleur, Howard Salis, Ayaan Hossain
Equalizer Circuits Provide Constant Gene Expression Regardless of Plasmid Copy Number in Mammalian Cells
Jihwan Lee, Jin Yang, Michelle Land, Shujuan Lai, Oleg Igoshin
Single-Cell and Single-Transcript Metrology for Engineering Biology
Jayan Rammohan, Steven Lund, Nina Alperovich, Vanya Paralanov, Elizabeth A. Strychalski, David Ross
Development of a Synthetic Biotic, SYNB8802, for the Treatment of Enteric Hyperoxaluria
David Lubkowicz, Lauren Renaud, Philippa J. Reeder, Sarani Ghoshal, Nick Horvath, Christopher Bergeron, Courtney Chen, Michael James, Pat Cantarella, Mark Charbonneau, Ron Shmueli, JR Gao, Marja Puurrunen, Vincent Isabella, Mylene Perreault
Automated Sample-to-Sequencer Library Preparation Using Programmed Centrifugal Force, Pneumatic Force, and Temperature Control
Jimin Guo, Daniel Brassard, Teodor Veres, Maxence Mounier, Mojra Janta-Polczynski, Caroline Miville-Godin, Ana Pilar, Natalie Corneau, Denis Charlebois, Jason Ferreira
Programming Multicellular Genetic Circuits and Sequential Logic in Synthetic Microbial Consortia
Lauren B. Andrews, Brian Voke, Min Zeng
Developing the Chlamydomonas Reinhardtii Plastid As a Platform for Directed Evolution of Photosynthetic Proteins
Adam Daki, Sarah C Stainbrook, Rishik Ummareddy, Kevin Qu
Single Cell Chemical Imaging with Stimulated Raman Scattering for Biofuel Production Screening
Nathan Tague, Haonan Lin, Jonghyeon Shin, Jing Zhang, Jean-Baptiste Lugagne, Wilson Wong, Ji-Xin Cheng, Mary J. Dunlop
Directed Evolution of a Genetically Encoded Contrast Agent for Ultrasound
Robert C. Hurt, Katie Wong, Daniel P. Sawyer, Ramya Deshpande, David R. Mittelstein, Mikhail Shapiro
Neutralization of Competition in Crispri Circuits Via dCas9 Feedback Regulator
Hsin-Ho Huang, Massimo Bellato, Yili Qian, Lorenzo Pasotti, Paolo Magni, Domitilla Del Vecchio, Pablo Cárdenas
Application of Natural RNA Regulators to Tune Biosynthesis of Nanoparticles for Enhanced Material and Functional Properties
Angela Chen, Julia Hernandez-Vargas, Runhua Han, Orlando Cortazar-Martinez, Natalia Gonzalez, Sonia Patel, Benjamin Keitz, Gabriel Luna-Barcenas, Lydia Contreras
Activating Silent Biosynthetic Gene Clusters in Streptomyces Spp. with Crispri
Andrea Ameruoso, James Chappell
Listen to DAD (Data-optimized Assembly Design) When Constructing High-Complexity Golden Gate Assembly Targets
John M. Pryor, Vladimir Potapov, Nilisha Pokhrel, Gregory J. S. Lohman
Macroscopic De-Novo Engineered Living Materials
Sara Molinari, Robert Tesoriero, Caroline Ajo-Franklin, Jayashree Soman
Using Qualitative Data for Quantitative Dynamics Estimation in Systems Biology
Jia Lu, Yuanchi Ha, Lingchong You, Teng Wang, Andrea Weiss
Protocell Arrays for Simultaneous Detection of Diverse Analytes
Yan Zhang, Taisuke Kojima, Ge-Ah Kim, Monica McNerney, Shuichi Takayama, Mark Styczynski
Temperature-Responsive Optogenetic Probes of Cell Signaling
Lukasz Bugaj, William Benman, Erin Berlew, Hao Deng, Caitlyn Parker, Ivan Kuznetsov, Arndt Siekmann, Brian Chow, Bomyi Lim
Engineering a Programmable Split-Ribozyme Platform for Detecting RNA in Living Cells
James Chappell, Lauren Gambill
Automated Culturomics Enables Deep Strain Isolation and Analysis of Personalized Gut Microbiomes
Yiming Huang, Harris Wang, Ravi U. Sheth
Cas9-Mediated Random Access in DNA Data Storage
Nicolas Cardozo, Karen Zhang, Jeff Nivala, Luis Ceze, Karin Strauss, Delaney Wilde, Charlie Anderson
A Synthetic Chromatin Reader-Effector Activates Key Silenced Tumor Suppressor Genes in Triple Negative Breast Cancer Cells
Natecia L. Williams, Cara Shields, Lauren Hong, Karmella Haynes
Engineering of Rare Earth Binding Proteins for Greener Extractions
Zachary E. Reinert, Chia-Suei Hung, Andrea R. Poole, Daria Perminova, Kelsey Gomez-Santos, Kevin Hinkle, Rajiv Berry
A GPCR-Based Yeast Biosensor for Biomedical, Biotechnological and Point-of-Use Cannabinoid Determination
Karel Miettinen, Sotirios C. Kampranis, Nattawat Leelahakorn, Aldo Almeida, Lukas R. Hansen, Yong Zhao, Soren Bak, Dan Staerk
Automated Design of Genetically-Encoded Protein-Sensing Riboswitches in a Cell-Free Expression System
Grace E. Vezeau, Lipika R. Gadila, Howard Salis
Anaerobic Conditioning of E. coli cell Lysate for Enhanced in Vitro protein Synthesis
Denis Tamiev, Jared Dopp, Nigel Reuel
Optimizing Nanoporeters for Multiplexable Mammalian Reporting Systems
Aerilynn Nguyen, Delaney Wilde, Jeff Nivala
Using Newly-Identified Epigenetic Reader-Effector BAHCC1 to Engineer a H3K27me3-Binding Transcriptional Activator
Paige Steppe, Karmella Haynes
Fabrication and Cross-Chassis-Characterisation of Artificial Promoters and 5´ Untranslated Regions in Vibrio Natriegens and Escherichia coli
Lisa Tietze
Using Metabolic Network Modeling to Design an Escherichia coli strain with Enhanced Outer Membrane Vesicle Production
Héctor Alejandro Ruiz-Moreno, Juan Daniel Valderrama-Rincon, Andrés F. González
A Targeted Genome-Wide Approach to Elucidate and Control Bacterial Adhesion to Physicochemically Diverse Biomaterials
Stephanie Call, Brandon Ugbesia, Vanessa Vu, Lauren B. Andrews
Yeast Biosensors for Cyclic Peptide Drug Discovery By Directed Evolution
Louis H. Scott, Michael Gossing, Verena Siewers, Florian David, Mark J. Wigglesworth, Andrew M. Davis
Expanding Nature’s Catalytic Toolbox with Artificial Metalloenzymes
Tobias Vornholt, Markus Jeschek, Sven Panke, Thomas R. Ward
Enhanced Regulation of Prokaryotic Gene Expression By a Eukaryotic Transcriptional Activator
Jonathan Emmons
Fabio: Fatty Acid Biosynthesis: Inducible, Orthogonal
Garima Goyal
Automated Metabolic Rewiring Design for Optimized Succinate Production in Saccharomyces Cerevisiae
Giuseppe Nicosia, Jole Costanza, Giorgio Jansen, Matteo Nicolò Amaradio, Xena Pappalardo
Towards Dynamic and Complex RNA Circuits: A Novel Approach to Address Retroactivity with Positive Feedback Insulation
Baiyang Liu, James Chappell