2024 AIChE Annual Meeting

Session: Drug and Gene Delivery II: Investigations towards Neuro & the Brain

This session will explore advances in drug and gene delivery that have specific applications towards the nervous system, namely the brain and neurons.

Co-Chairs

Rajarshi Chattaraj, University of Pennsylvania
Michelle Teplensky, Northwestern University
Lisa Volpatti, University of Chicago

Presentations

12:30 PM

(684a) Invited Talk: Delivery of Mitochondria-Containing Extracellular Vesicles to the Blood-Brain Barrier
Devicka Manickam

01:10 PM

(684b) Engineered Cocktails of Alpha-Particle Nano-Radiotherapy and Low-Dose Chemotherapy for Treatment of Glioblastoma
Aira Sarkar, Rajiv Ranjit Nair, Pooja Hariharan, Kathleen Gabrielson, Rangaramanujam Kannan, Stavroula Sofou

01:28 PM

(684c) Regionally-Dependent Cellular and Mechanistic Signatures for Screening Neuroprotective Therapies in the Preterm Injured Brain
Zheyu Jin, Kylie Corry, Olivia Brandon, Hawley Helmbrecht, Daniel Moralejo, Sarah Kolnik, Sandra Juul, Thomas Wood, Elizabeth Nance

01:46 PM

(684d) Ultrasound-Responsive Microbubbles As Carriers of Xenon and Argon Gas for the Treatment of Traumatic Brain Injury
Rajarshi Chattaraj, Misun Hwang, Chandra Sehgal, Daeyeon Lee

02:04 PM

(684e) Extracellular Vesicles Incorporating Retrovirus-like Capsids for the Enhanced Packaging and Systemic Delivery of mRNA into Neurons
Wenchao Gu, Sijin Luozhong, Simian Cai, Ketaki Londhe, Nadine Elkasri, Robert Hawkins, Robert Hawkins, Zhefan Yuan, Kai Su-Greene, Yujie Yin, Mache Cruz, Yu-Wei Chang, Wenchao Gu, Chunyan Wu, Changwoo Seo, Akash Guru, Wenting Gao, Chris Schaffer, Nozomi Nishimura, Richard Cerione, Qiuming Yu, Melissa Warden, Robert Langer, Shaoyi Jiang

02:22 PM

(684f) Nano-Formulated Curcumin Uptake and Biodistribution in the Fetal Growth Restricted Newborn Piglet Brain
Nuo Xu, Julie Wixey, Kirat Chand, Elizabeth Nance

02:40 PM

(684g) Exploring (some of) the Empowerment Mechanisms of Alpha-Particle Radiopharmaceutical Therapy By Low-Dose Chemotherapy in Breast Cancer Brain Metastasis
Pooja Hariharan, Rajiv Ranjit Nair, Aira Sarkar, Rangaramanujam Kannan, Daniele Gilkes, Stavroula Sofou