2017 Annual Meeting

Session: Process Intensification and Advanced Control of Pharmaceutical Processes

This session will include talks that demonstrate the use of advanced control approaches and process intensification techniques applied in drug substance and drug product manufacturing.

Chair

Dimitrios Gerogiorgis, University of Edinburgh

Co-Chair

Zoltan K. Nagy, Purdue University

Presentations

03:15 PM

(623a) Technoeconomic Evaluation of Cyclosporine Crystallisation Intensification Using a Cascade of M.S.M.P.R. Crystallisers
Samir Diab, Dimitrios Gerogiorgis

03:36 PM

(623b) Application of Advanced Process Control Tools in Continuous Processing
Stephan Sacher, Jakob Rehrl, Julia Kruisz, Otto Scheibelhofer, Isabella Aigner, Patrick R. Wahl, Michael Martinetz, Johannes G. Khinast

03:57 PM

(623c) Nonlinear First-Principle Model-Based Control of a Continuous Pharmaceutical Manufacturing Process
Thomas O'Connor, Nima Yazdanpanah, Naresh Pavurala, Sonal Mazumder, Muhammad Ashraf, Celia Cruz, Cassandra Taylor, Xiaoming Xu

04:18 PM

(623d) A Fault-Tolerant Control Design for Real-Time Release in Continuous Manufacturing of Solid Dose Using Direct Compaction
Mariana Moreno, Qinglin Su, Jianfeng Liu, Sudarshan Ganesh, Yasasvi Bommiready, Marcial Gonzalez, Gintaras V. Reklaitis, Zoltan K. Nagy, Thomas O'Connor, Geng Tian

04:39 PM

(623e) Intensified Crystallization of Sulfathiazole and Sulfanilamide By Direct Co-Crystal Assembly
Kuan-Lin Yeh, Tu Lee

05:00 PM

(623f) Direct Co-Crystal Assembly from Synthesis to Co-Crystallization
Ya-Chi Fan, Hung Lin Lee, Tu Lee

05:21 PM

(623g) Continuous Preparation of 1:1 Haloperidol-Maleic Acid Salt By a Novel Solvent-Free Method Using a Twin Screw Melt Extruder
Hung Lin Lee, Jaydip M. Vasoya, Marilia de Lima Cirqueira, Kuan-Lin Yeh, Abu T. M. Serajuddin, Tu Lee