Many people view the conduct of a HAZOP/LOPA to address regulatory requirements as a chore, and stop there. However, the implementation of a quality HAZOP/LOPA has the potential to provide a framework for addressing numerous safety and operational optimization issues at plants, including the formulation/refinement of the Mechanical Integrity Program. The purpose of this paper is to focus on the mechanical integrity program, illustrate how a quality HAZOP/LOPA can support the effective implementation of some of the new requirements for California Refineries, and optimize key elements of an effective Mechanical Integrity Program, e.g.: