2025 AIChE Annual Meeting

Session: Engineering Cancer: Chemical Engineering Contributions to Cancer Biology and Treatment

Chemical engineers are transforming cancer research by tackling key challenges such as drug resistance, metastasis, immune evasion, and tumor microenvironment interactions. This session will explore contributions in areas including exosome-based cancer diagnostics, mass transport limitations in tumors, dormancy and recurrence mechanisms, immunotherapy strategies, and computational modeling of cancer progression.

Chair

Thomas Zangle, University of Utah

Co-Chairs

Henry Squire, University of California- Berkeley
Joshua Ramsey, Oklahoma State University
Swomitra Mohanty, University of Utah

Presentations

03:30 PM

(239a) Engineering Endothelial Leakiness with Inorganic Nanomaterials
David Leong

03:45 PM

(239b) Magnetic Characterization, Isolation, and Detection of Breast Cancer Stem Cells Via Label-Free Magnetophoresis
Linh Tran, Karla Paz Gonzalez, Reagan Farrell, Kuan Hui Chen, Jeffrey Chalmers, Jenifer Gomez Pastora

04:00 PM

(239c) Engineering and Characterization of Cells for the Expression of Surface Receptors and Release on Extracellular Vesicles (EVs)
Samuel Orozco, John P. Nolan

04:15 PM

(239d) Dielectric Signatures of Red Blood Cells from Pancreatic Cancer Patients Under Simulated Microgravity
Alexa Bostic, Sai Deepika Reddy Yaram, Soumya Srivastava

04:30 PM

(239e) mRNA-Lnp Cancer Vaccines Adjuvanted with Co-Stimulatory Molecules Turn Cold Tumors Hot
Amy Laflin, Yiwei Feng, Angelica Bernal Penaloza, Erica Wagner, Ronit Kumar, Shaoyi Jiang

04:45 PM

(239f) Plasmid DNA Vaccine for Post-Surgical Immunotherapy Against Murine Melanoma
Trishita Chowdhury, Vanshika Singh, Sudhakar Godeshala, Muhammad Raisul Abedin, Sannia Hagag, Jordan Yaron, Kaushal Rege

05:00 PM

(239g) Metabolic Engineering of Cell Therapy: Mannose-Enhanced Biomanufacturing for Improved Cellular Therapy Products with Superior Anti-Tumor Function
Yapeng Su, Yajing Qiu, Ermei Xie, Hongcheng Cheng, Jing Du, Yue Xu, Xiaoli Pan, Zhe Wang, Daniel Chen, Hong Zhu, Philip Greenberg, Guideng Li