2025 AIChE Annual Meeting

Session: Biomolecular Engineering: Therapeutic Engineering and Disease Modeling

This session focuses on engineering immune responses, antimicrobial strategies, and disease-relevant modeling using both experimental and computational approaches. Talks will include methods to modulate cell signaling, predict therapeutic targets, and enhance treatment specificity.

Chair

Carl Denard, University of Texas at Austin

Co-Chairs

Piyush Jain, University of Florida
Ross Thyer, University of Texas at Austin

Presentations

11:30 AM

(686a) Invited Talk: Targeting Glycans for Cancer Immunotherapy
Jessica Stark

12:06 PM

(686b) Engineering Immune Tolerance through a Novel Strategy for Dendritic Cell Modulation
Sihan Jia, Peter Deak

12:24 PM

(686c) Assessing Essential and Defensive Gene Co-Targeting to Enhance CRISPR Antimicrobial Efficacy Against Staphylococcus Aureus
David Dooley, Cong T. Trinh

12:42 PM

(686d) Molecular Modeling of TREM2 and sTREM2 Reveals Mechanisms of Microglial Signaling and Therapeutic Potential in Alzheimer’s Disease
David Saeb, Emma Lietzke, Emma C. Aldrich, Daisy Fuchs, Kimberley D. Bruce, Kayla G. Sprenger

01:00 PM

(686e) Development of a Computational Tool for the Identification of Viable Regions of Proteins to Target for Binding
John Oyinbo, Jacinta Amoakoa-Djam, Robert J. Pantazes

01:36 PM

(686g) Optogenetic Control of BMP Signaling Dynamics in Cells and Tissues
Hung-Yuan Chen, Gregory Reeves