2024 AIChE Annual Meeting

Session: Poster Session: Pharmaceutical Discovery, Development, and Manufacturing

Please join us for a poster session to highlight work focused on Pharmaceutical Discovery, Development, and Manufacturing.

Chair

Michael Lovette, Eli Lilly

Presentations

(184ab) Efficient Multi-Objective Bayesian Optimization of Chemical Reactions
Vidhyadhar Manee, Thomas Tampone, Dauzhan Yerkozhanov, Zhen Lei, Frederic Buono
(184g) Viral Filtration Optimization for Challenging Non-Mab Exhibiting Rapid Flux Decay
Daniel Gendy, Peter Liu, Samantha San, Lauren Rockwell
(184e) Precipitant Surprise! Investigation and Mitigation of Media Precipitation during Scale-up and Technology Transfer
Benjamin Hawkins, Brian Thatcher, Caitlin Wasilko, Dixit Raiyani
(184i) Comparison Among Lnp, PNP and Exosomes for Gene Delivery to Treat Triple-Negative Breast Cancer
Tanvi Varadkar, Kai Chen, Jiashuai Zhang, Zhuoxin Zhou, Lufang Zhou, X. Margaret Liu
(184aa) Advancing Kinetic Parameter Estimation: A Metabolism-Informed Variational Bayesian Inference Approach
Mariana Monteiro, Ranjith Chiplunkar, Max Mowbray, Cleo Kontoravdi
(184r) Antioxidants Supplementation to Cell Culture Media and Feed Influences Productivity and Product Quality of Mabs from CHO Cells
Erin Kotzbauer, Suyang Wu, Yen-An Lu, Kyle Devenney, Karen (Min-yea) Lee, Venkata S. Tayi
(184l) High-Throughput Experimentation Reveals Scope and Limitations of Selective Phosphine Reductants and Enables One-Pot Mab Reduction/Conjugation
Cuixian (Trisha) Yang, Marion Emmert, Eugene Kwan, Rebecca A. Chmielowski, Bruce Kilgore, Zachary Vanaernum, Cecilia Bottecchia, Rodell Barrientos, Monica Haley, Kelly Raymond, Michael Rauscher, Zachary D. Dunn, Jay Desai
(184n) Thermodynamics Analysis with Molecular Informatics for Understanding Pharmaceutical Cocrystallization Promoted in Fatty Acid Media
Yuna Tatsumi, Yasuhiko Orita, Yusuke Shimoyama
(184x) Hybrid Modelling for Semi-Permeable Membranes: A Water Vapor Transmission Rate (WVTR) Stability Estimation.
Mandakini Padhi, Nallasivam Angannan, Jean-Sebastien Simard
(184o) Risk-Based Quality Control for the Safe and Efficient Biotechnological Batch Production of Lactic Acid
Austin Braniff, Dylan Miller, Beatriz Dantas, Sahithi Srijana Akundi, Yuanxing Liu, Shayan Niknezhad, Faisal Khan, Efstratios Pistikopoulos, Yuhe Tian
(184v) Data 1.0 before Pharma 4.0: From R&D to Supply Chain
Amy Wagner, Nima Yazdanpanah
(184z) Spray Dryer Design for Robust Manufacturing of Amorphous Solid Dispersions
Gabriele Sadowski, Christian Lübbert
(184c) Need Big Particles but Have No Time? Rapid Development & Scale-up of Spray Drying to Control Particle Size
David Goundie, Benjamin Hawkins
(184b) Polysaccharide Charge Reduction For Conjugation Vaccine Modernization
Megan McCarthy, Katherine Phillips, Christopher Brennan
(184p) Impact of Droplet Evaporation on Polymorphism of Suberic Acid
Sheriff Anofi, Ryan Snyder
(184w) Federated Hierarchical Tensor Networks: A Collaborative Learning Quantum AI-Driven Framework for Healthcare
Amandeep Bhatia, David E. Bernal Neira
(184j) Improving Numerical Methods for Bioreactor Process Simulation and Parameter Estimation
Taehun Kim, Miguel Angel Valderrama-Gomez, William Heymann, Juliane Glaser, Matthew Demers, Sidra Xu, Elcin Icten Gencer, Fabrice Schlegel, Pablo Rolandi
(184ad) Toxic to Treatment: Bioprospecting in Battery Waste Rhizospheres for Novel Therapeutics Against High Priority Antibiotic-Resistant Pathogens
Kylah Dalgleish, John Unuofin, Luke Invernizzi, Michael Daramola, Samuel Iwarere
(184ac) Scaling Organic Electrosynthesis: The Crucial Interplay between Mechanism and Mass Transport
Zachary Oliver, Dylan Abrams, Luana Cardinale, Greg Beutner, Seb Caille, Benjamin M. Cohen, Lin Deng, Moiz Diwan, Antonio Ferretti, Michael Frederick, Kaid Harper, Dan Lehnherr, Tessa Myren, Kyle Quasdorf, Melda Sezen-Edmonds, Kevin Stone, Shannon S. Stahl, Marcel Schreier
(184s) Diffusion of Viral Vectors Informs Continuous Manufacturing with Aqueous Two-Phase Extraction
Seth Kriz, Sydney Dankert, Idris Tohidian, Caryn Heldt
(184h) Particle Jamming upon Administration of Long-Acting Injectable Crystalline Drug Suspensions
Ziwan Xu, Kavin Kowsari, Kartik Bomb, Latevi Lawson, Faustin Arevalo, Ashley Johnson
(184k) Gaussian Process Regression Modeling to Predict ?/?-Peptide Selectivity for Antifungal Drug Development
Joshua Richardson, Douglas Chang, David M. Lynn, Sean P. Palecek, Reid Van Lehn
(184d) Empirical Calculations for Reliable Batch Blending Operation Scale-up in Pharmaceutical Manufacturing
Kanishka Ghosh, Rajesh Kulkarni, Joshua Hanson, Joel Francis, Maitraye Sen
(184t) Unlock Bioprocessing Capacity: A Comparative Study Focused on Intensified Downstream Processes
Xuan Han, Avani Ramachandra, Dan McNamara, Paul Gramlich
(184q) Development of a Lab-Scale Fluid Bed Granulation Process within a Semi-Continuous Manufacturing Workflow
Sydney Butikofer, Marly Jo Santos Colón, Joshua Hanson, Jonathan Brett Wade, Zhanjie Liu, Shashwat Gupta
(184u) Machine Learning and Artificial Intelligence for Formulation Optimization
Howard Stamato, Daniela Blanco