2020 Virtual AIChE Annual Meeting

Session: In-silico Tools for Integrated Process Design and Manufacturing

Chair

Sarang Oka, Hovione

Co-Chair

Shankali Pradhan, Vertex Pharmaceuticals Incorporated

Presentations

08:00 AM

(377a) Design Space Via Symbolic Computation
Fei Zhao, Ignacio Grossmann, Salvador Garcia-Munoz, Stephen D. Stamatis

08:15 AM

(377b) A Multi-Scale Hybrid Modeling Approach for Continuous Pharmaceutical Unit Operations
Pooja Bhalode, Marianthi Ierapetritou

08:30 AM

(377c) Integrated Use of Digital Twin-Based Framework for the Development of a Lomustine Manufacturing Pathway
Daniel Laky, Jaron Mackey, Ahmed Mufti, Daniel Casas Orozco, Gintaras Reklaitis, Carl Laird, Su-Lin Lee, Mesfin Abdi, Xin Feng, Erin Wood, Zoltan K. Nagy

08:45 AM

(377d) Digital Design of End-to-End Manufacturing Process for Mefenamic Acid Using Mechanistic Modeling
Cameron Brown, Niall Mitchell, Frederik Doerr, John McGinty, Magdalene Chong, Murray Robertson, Elke Prasad, Sara Ottoboni, Wei Li, Guillermo Jimeno, Patricia Marce Villa, Chris Rielly, Chick Wilson, Alastair J. Florence

09:00 AM

(377e) Digital Design of an End-to-End Drug Manufacturing Process Using Mechanistic Modeling
Jonathan Meyer, Amit Goda, Filipe Calado, Renato Wong, Ananya Chowdhury, Dana Barrasso, Edward Close, Niall Mitchell, Sean Bermingham, Sélim Douieb, Ugo Cocchini

09:15 AM

(377f) Digital Design of a Dry Granulation-Based Drug Product through Integrated Manufacturing Process and Product Performance Modeling
Ananya Chowdhury, Parind Desai, Boung Wook Lee, Rachel Apfelbaum, Yash Melkeri, Dana Barrasso, Edward Close

09:30 AM

(377g) A Mechanistic Model-Based Digitalisation Framework for Continuous Manufacturing Processes
Li Ge Wang, David Slade, Chalak Omar, James D. Litster, Agba D. Salman