2016 AIChE Annual Meeting

Session: Poster Session: Pharmaceutical

Poster Session: Pharmaceutical

Chair

Albrecht, J., Bristol-Myers Squibb Co.

Co-Chair

Nagy, Z. K., Purdue University

Presentations

03:15 PM

Material Science
(233t) Continuous Manufacturing of Co-Crystals in Twin Screw Extruder: A Case Study
Darwish, S., Shaikh, R., Kuhs, M., Croker, D., Walker, G.
Green Processing
(233n) Fault-Tolerant Control Design and Risk MAP Based Resiliency Analysis of Continuous Solid Dose Manufacturing
Moreno, M., Ganesh, S., Su, Q., Giridhar, A., Reklaitis, G., Nagy, Z. K.
(233z) Wet Granulation-Induced Polymorphic Transitions in Piracetam: Raman Spectroscopy As a Potential in-Situ Process Analytical Tool
Kollamaram, G., Kelly, C., Croker, D., Walker, G.
Drug Delivery
(233h) A Comprehensive Statistics-Based Approach to Proactive Process Analysis Including Multivariate Analysis Methods
Koynov, S., Adack, P., Sun, J., McCurdy, C., Crowther, O., Cleary, M., Ruane, A., Carr, D., O'Brien, E.
(233az) Dissolvable Microcarriers for Efficient Cell Production and Recovery
Zhou, Y., Weber, J. L., Krebs, K., Hervy, M., Pecheul, M., Walerack, C., Henry, D., Bear, M. M., Caracci, S.
Pharmacokinetics
Drug Discovery
(233y) PAT Application in Expedited Development of Multi-Step Chemical Syntheses of Active Compounds
Hebrault, D., Haddad, N.
(233af) The Effect of Particle Engineering on the Processing and the in Vitro Performance of Inhalation Blends in Dry Powder Inhalers
Faulhammer, E., Zellnitz, S., Khinast, J. G., Paudel, A., Wutscher, T.
(233ay) The Utilization of Amino Acid Consumption Rate Assessment As a Tool for CHO Clonal Stability Evaluation.  
Brodean, E., Seletsky, A., Good, M., Ling, W. L.
(233ax) Process Innovation and Optimization of a Commercial Cell Culture Process
Agastin, S., Sivakollundu, S., Savard, J., Gregoire, S.
(233aw) Feasibility Analysis of Flowsheet Models in Continuous Pharmaceutical Manufacturing Processes Considering the Effects of Noise
Wang, Z., Escotet-Espinoza, M. S., Singh, R., Muzzio, F. J., Ierapetritou, M. G.
(233c) Integrated Flowsheet Modeling and Experimental Validation in Dry Granulation for Pharmaceutical Excipients: Effects of Changes in Roller Compactor Parameters on Granules
Park, S. Y., Galbraith, S., Cha, B., Liu, H., Huang, Z., Lee, H. W., Yoon, S.
(233x) Process Understanding for Antisolvent Cocrystallization Based on Near-Infrared and Raman Spectroscopic Measurements
Choi, G. J., Cho, M. Y., Lee, M. J.
(233i) Design of Nonlinear Observer for State Estimation of a Bioreactor
Pan, X., Jaladi, T., Raftery, J., DeSessa, M., Karim, M. N.
(233ag) Characterization of Compaction Behaviour of Powders in Solid-Dosage Manufacturing Using Finite Element Analysis
Kumar, A., Dhondt, J., Bertels, J., Klingeleers, D., Gernaey, K. V., Nopens, I., De Beer, T.
(233e) Computational Fluid Dynamics (CFD) Guided Scale up of Cell Culture Bioreactors from Bench to Pilot to Commercial Scale
Tran, W., Chaudhary, G., Schaefer, J. E., Hasenfus, E., Wucherpfennig, T., Bock, D., Lin, H.
(233aq) Gender-Dependent PBPK Modeling
Androulakis, I. P., Scherholz, M., Sinko, P. J., Ierapetritou, M., Hartmanshenn, C.
(233l) Model-Based Process Analysis in Continuous Manufacturing of Pharmaceuticals: Calibration of a Fluid Bed Dryer Model
Ghijs, M., Nopens, I., De Beer, T., Vanhoorne, V., Gernaey, K. V., Van Hauwermeiren, D., De Leersnyder, F., Vercruysse, J., Mortier, S. T. F. C., Cappuyns, P.
(233au) Powder Tester Comparison to Predict Discharge Rate from Hoppers and Filling Tablet Press Dies
Theuerkauf, J., Fan, Y., Horton, A., Kodam, M., Jacob, K.
(583a) Spray Drying of Ternary Solid Dispersions of Ibuprofen and Indomethacin with Superior Physical Stability
Albadarin, A. B., Mahboubah, P., Schaller, B., Ziaee, A., Walker, G.
(233m) Exploring the Design Space of a Novel Tablet Coating Process in a Continuous Manufacturing Line
Birkmire, A., Cunningham, C., Gilliam, S.
(233o) Characterization of Mixing and Heat Transfer in Continuous Lab Scale Reactors
Salan, J. S., am Ende, D.
(233p) Development of a Model Predictive Tool for Continuous Manufacturing of Solid Oral Dosage Forms Via Roller Compaction
Schaller, B., Mahboubah, P., Cronin, P., Ziaee, A., Albadarin, A., Croker, D., Collins, M., Walker, G.
(233a) Chemical Engineering Principles in Oral Solid Dosage Process Development-Where Are We?
Shi, W.
(233q) Application of Model-Predictive Control to a Feeding Blending Unit
Rehrl, J., Kruisz, J., Sacher, S., Horn, M., Khinast, J. G., Aigner, I.
(233j) Effect of Formulation Hydrophobicity on the Wet Granulation Growth Behavior
Candelaria, M.
Pharmaceutical Manufacturing
(233aj) Green Synthesis of Carboxylic Acids from Ethyl Acetates Derivatives Using K2CO3 Under Microwave Irradiation
Hernández-Fernández, E., Hernández-Fernández, J., Rodríguez-Torres, V., Tiempos-Flores, N., López-Cortina, S.
(233ai) Systematic Technoeconomic Comparison of Separation Solvents for Green Continuous Pharmaceutical Manufacturing of Diphenhydramine
Diab, S., Gerogiorgis, D.
(233ah) Green Synthesis of Acetamides from Ethyl Acetates Under Base Free Conditions and Microwave Irradiation
Tiempos-Flores, N., Hernández, E., López Cortina, S., Medina, Y.
(233as) Screening a Library of Commercially Available Compounds for Drugs with Novel Anti-Biofilm Activity
Ramasubramanian, A., Lopez-Ribot, J., Leung, K., Srinivasan, A., Abercrombie, J., Torres, N.
(233u) Continuous Wet Granulation in a Twin Screw Extruder: Effect of Process Variables on Residence Time Distribution and Granule Characteristics
Albadarin, A., Kuhs, M., Kollamaram, G., Darwish, S., Shaikh, R., Shirazian, S., Croker, D., Walker, G., Zeglinski, J.
(233av) A Small Volume Continuous Facility for GMP API Manufacture
Spencer, R.
(233ad) Controlling amorphization versus crystallization of carbamazepine nanoparticles using a supercritical-assisted spray drying process
Padrela, L., Ryan, K. M., Long, B.
(233an) Evaluation of the Therapeutic Potential of FOXC1 Knockdown for Treatment of Basal-Like Breast Cancers
Mott, L. A.
(233aa) Real-Time Monitoring and Ejection of out-of-Spec Tablets Via NIR Chemical Imaging
Wahl, P. R., Hauseder, G., Sacher, S., Kerschhaggl, M., Khinast, J. G.
(233k) Residence Time Distribution Analysis for a Hot Melt Granulation Process Using Positron Emission Particle Tracking and NIR and Raman Spectroscopic Probes
Wray, P., Bergqvist, K., Jones, J., Vernon, M., McGeorge, G., Dennis, A.
(233ar) Virtual High-Throughput Screening Pipeline: Limitation Characterization and Application to Different Targets
Chen, J. J., Visco, D. Jr.
(233ap) Prediction of Formulation Effects of Continuously Formulated Solid Oral Dosage Forms on Bioavailability Using PBPK Modeling
Hartmanshenn, C., Androulakis, I. P., Ierapetritou, M. G., Sinko, P. J.
(233ao) Predicting the In Vivo Performance of Amorphous Solid Dispersions Based on Molecular Descriptors and Statistical Analysis
Duarte, Í., Henriques, J., Pinto, J. F., Temtem, M.
(233am) Modeling and Simulation Efforts in Scale up of Sustained Release Microspheres
Mehan, R., Garikipati, S. J., David, B. K., Partani, Y., Palaparthi, R.
(233d) Multivariate Statistical Process Control for the Continuous Manufacturing of Solid Oral Dosage Forms
Garcia-Munoz, S., Shi, Z., Hanson, J.
(233b) Combined Task Bayesian Optimization for Efficient Scale-up and Technology Transfer
Yoshizaki, R., Kano, M.
(233r) Behaviour of Magnesium Stearate in Continuous Feeding
Peddapatla, R. V. G., Blackshields, C. A., Cronin, M. F., Crean, A.
(233g) Modelling Approaches to Spray Drying Process Development, Scale-up and Troubleshooting
Valente, P., Duarte, Í., Neves, F., Temtem, M.
(233v) Development and Optimization of a Mixed Suspension Mixed Product Removal (MSMPR) Crystallization Process Incorporating Wet-Milling 
Yang, Y., Papageorgiou, C. D.