Next generation DNA synthesis applied in Metabolic Pathway Synthesis and Library Assembly

Since the birth of synthetic biology in 2000, metabolic engineering and synthetic biology research have made increasingly huge progress on high value-added natural products. The synthesis and construction of metabolic pathways as well as diverse DNA assembly technologies play a fundamental role in microbiology, biochemistry, and many other relevant fields. Based on the function of metabolic pathways, various genes combine together to get high value-added biological materials, drug or drug intermediates. Metabolic Pathway Synthesis has serviced in construction of synthesis pathway for butanol, Artemisinic acid, paclitaxel precursors, the baline and hydrocodone drug precursors. With the rapid development of gene synthesis and assembly technology, especially next generation DNA synthesis technology, the price of large DNA fragment or plasmid synthesis is decreasing year by year, providing opportunities and access for synthetic biologists and metabolic engineers to more easily conduct their research. Over the last 10 years, the continuous development of high flux and automated highthroughput screening methods significantly help to improve the convenience and simplicity of the late screening of library technology, provide more beneficial tools for metabolic engineering and synthetic biology research, and play an important part in chemical synthesis, pharmacology, agricultural, and environmental fields. Synbio Technologies is a DNA technology company. Our streamlined synthesis platforms are proper for accurate, fast, high-throughput gene synthesis; with the strong long fragments gene or genome assembly platform to achieve the precise and rapid assembly of metabolic pathway polygenes; with E. coli and yeast CRISPR / Cas9 genome editing platform to achieve the pathways in the microbial genome of the fixedpoint integration to form a stable cell line. Synbio Technologies Metabolic Pathway Synthesis platform has completed more than 50 metabolic pathways to achieve various customized services with our highly flexible platforms.