International Conference on CRISPR Technologies

Session: Genome editing and gene regulation in human health

Presentations

01:15 AM

Gene Repression Via CRISPR-Assisted Modification of Specific Chromatin Marks

Liad Holtzman, Jay Rathinavelu, Charles A. Gersbach

01:40 AM

CRISPR-Based Synthetic Gene Circuits for Controllable Gene Therapies

Samira Kiani

02:05 AM

RNA Secondary Structure Increases the Specificity of Class 2 CRISPR Effectors

Daniel Dewran Kocak, Eric A. Josephs, Jennifer B Kwon, Shaunak S. Adkar, Christopher J. Fitzgibbon, Tyler S. Klann, Pratiksha I. Thakore, Piotr E. Marszalek, Charles A. Gersbach

02:30 AM

Engineered Stem Cell Models to Reconstitute Kidney Function and Disease

Samira Musah, Donald E. Ingber, George M Church

02:55 AM

Computational Selection of CRISPR/Cas9 Guide-RNAs to Target Highly Variable Integrated HIV-1 Provirus Using Next Generation Sequencing

Will Dampier, Michael Nonnemacher, Cheng-Han Chung, Alexander Allen, Neil Sullivan, Vanessa Pirrone, Katherine Kercher, Shendra Passic, Jean Williams, Brian Wigdahl

12:00 PM

A Novel Cas9 Mutant Confers Reduced Off-Target Gene Editing While Maintaining on-Target Potency

Michel Cannieux, Garrett Rettig, Bernice Thommandru, Ashley Jacobi, Michael Collingwood, Mollie Schubert, Mark Behlke, Christopher Vakulskas, Jessica Lister

12:25 PM

Fluorescent Guide RNAs for Understanding Grnas Expressed from Pol II Promoters

David Menn, Mo Ebrahimkhani, Xiao Wang, Samira Kiani

12:50 PM

Enhancer Composition and Dosage Control Developmental Gene Expression

Anja Will, Giulia Cova, Marco Osterwalder, Wing-Lee Chan, Lars Wittler, Norbert Brieske, Verena Heinrich, Jean-Pierre De Villartay, Martin Vingron, Axel Visel, Eva Klopocki, Darío Lupiáñez, Stefan Mundlos