5th Conference on Constraint-Based Reconstruction and Analysis (COBRA 2018)

Session: Applications in Medicine

Presentations

09:00 AM

Urea cycle dysregulation, emerging pyrimidines mutation bias and enhanced response to immunotherapy in cancer

Eytan Ruppin, Joo Sang Lee

09:30 AM

Modeling Physiological Responses to Stress: Metabolism of Fasting and Acetaminophen-Induced Liver Damage in the Laboratory Rat

Anders Wallqvist, Venkat Pannala, Martha Wall, Shanea Estes, Trenary Irina, O’Brien Tracy, Printz Richard, Vinnakota Kalyan, Jaques Reifman, Masakazu Shiota, Jamey Young

09:45 AM

Differential Metabolic Functionality in Antibiotic-Resistant Pseudomonas aeruginosa Revealed with an Integrated Computational and Experimental Approach

Laura J. Dunphy, Jason Papin, Phillip Yen

10:00 AM

Model-Based Prediction of Functional SNPs Suggests Factors for Metabolic Diversity and Drug Resistance across Human-Associated Mycobacterium Tuberculosis

Jörg Stelling, Ove Øyås, Uwe Sauer, Andrej Trauner, Sonia Borrell, Mattia Zampieri, Sébastien Gagneux, Michael Zimmermann

10:15 AM

Synthetic Lethality in Cancer Research Via Genetic Minimal Cut Sets

Francisco J. Planes, Iñigo Apaolaza, Luis Vitores Valcárcel, Xabier Agirre, Felipe Prosper, Edurne San Jose