2014 Process Development Symposium
Mixing Is Empirical.
Empirical means: relying upon or derived from observation or experiment. The reasons for process development studies are the observations or experiments necessary to decide the effects of mixing on an application. Mixing studies can be conducted in the laboratory, pilot plant, or production. Each level of mixing study has its problems and benefits. The objectives of these studies are the determination of mixing limitations and the factors that influence those limits. Studies at different mixing conditions, as defined by mixer speed and impeller diameter or type, help establish limits and scale-up criteria. Success depends on correct interpretation of empirical results.