In-Line 3-Dimensional Image Analysis of Particulate Powers and Slurries

Many methods of particles size analysis are available to characterize powder and slurry distributions. Probably the most widely used instrumental methods are laser diffraction and dynamic light scattering. As part of complete characterization, the shape of the particles can offer information as to changes to chemistry, process variations, handling, transport and other causes of product variation. Further examination of these changes of shape can be determined by microscopy (Static Image Analysis – particle stationary) which while useful, can be time-consuming while having limitation as to number of particles examined and thus can have low statistical significance. As a result, it is desirable to have a large number of particles examined to lend statistical significance to the data. This is easily accomplished by automated image analysis in the dynamic mode (particles in motion). Particles in motion allow for 2-dimenional analysis, but in addition, can allow for 3-dimeional analysis as well. 3-dimensional analysis is particularly useful for obtaining information on particles that do not approximate a sphere or when agglomerates are present. The advantage of 3-dimenisional analysis and on-line image analysis in various industries for a wide range of products will be described.