In this study, a two-dimensional model is used to study the transfer phenomena occurred in the radial adsorber with consideration of heat effect, gas compressibility and dead volumes. The distributions of concentration, temperature and velocity in four possible configurations, CP-z, Cp-Π, CF-z, and CF-Π of a radial flow adsorber are investigated. As expected, the results visually show the evolution of process variables and their distribution. Some discussions of the effect of different configurations on variables distribution are made. The two-dimensional simulation is found to be very useful for a better understanding of the dynamic sorption and separation process in the radial adsorber.