2007 Spring Meeting & 3rd Global Congress on Process Safety

(8d) Application of Micro-Reactor Technology in Process Development

Author

Zhang, X. - Presenter, Johnson & Johnson Pharmaceutical Research & Development, L.L.C.


The microreactor technology is an efficient tool for kilogram scale syntheses in continuous mode and is particularly effective for hazardous reactions that do not allow scale up in conventional reactors. Applications to several classes of reactions including highly exothermic reactions, high temperature reactions, reactions with unstable intermediates and reactions involving hazardous reagents are discussed.