2025 AIChE Annual Meeting

Session: Biomolecular Engineering: Synthetic Biology and Genetic Engineering

This session highlights advances in tools for precise genetic control, including CRISPR systems, synthetic RNAs, and expanded genetic codes. Talks will showcase new molecular strategies to engineer gene expression and create novel functionalities across biological systems.

Chair

Carl Denard, University of Texas at Austin

Co-Chairs

Ross Thyer, University of Texas at Austin

Presentations

03:30 PM

Invited Talk: Biomolecular Engineering: Synthetic Biology and Genetic Engineering
James Carothers

04:06 PM

(24a) Nucleotide-Level Characterization and Improvement of Inducible Transcription Factor Promoters Using a High-Throughput Approach
Nicholas Sandoval, Nancy Kim

04:40 PM

(24c) Self-Amplifying RNA with Modified Nucleotides Improves Potency and Safety
Ting-Yu Shih, Joshua McGee, Jack Kirsch, Wilson Wong, Mark Grinstaff

04:56 PM

(24d) Nitration of a Foreign Antigen Via Genetic Code Expansion Increases In Vivo Immune Response
Christopher Mayhugh, Neil Butler, Emma Sudduth, Michael Trautmann-Rodriguez, Catherine Fromen, Aditya Kunjapur

05:12 PM

(24e) Understanding Non-Canonical Base Interactions through Mutational Analysis of the Lettuce Aptamer
Alexandra Adams, H. Tom Soh

05:28 PM

(24f) Design of a D-Amino Acid Peptide Mimic for Plant Biotechnology
Henry Squire, Pedro Alberto Valiente Flores, Teng-Jui Lin, Philip Kim, Markita Landry

05:44 PM

(24g) Eppi_Ddg: Efficiently Predicting Point Mutation Effects Using a Structure-Based Feature Space
Alan Richard, Robert J. Pantazes