This study presents a systematic methodology for the conceptual design of reactive distillation columns, integrating static analysis techniques to evaluate the feasibility of reaction-separation coupling. The approach is based on reactive residue curve maps (RRCMs) to determine feasible product separations and identify optimal column configurations. Additionally, a stepwise procedure is employed to incrementally introduce process complexity while maintaining thermodynamic consistency. The design strategy incorporates key considerations such as catalyst selection, reaction zone placement, and separation feasibility, ensuring an efficient and scalable intensified process. To validate the methodology, Aspen Plus® simulations are conducted to assess the impact of different design parameters on conversion rates and product purity. The proposed framework provides a structured approach for the development of intensified distillation processes, facilitating energy-efficient and sustainable production.
