Transitioning to a low-carbon future requires integrating clean energy, sustainable materials, and transportation systems. As electric vehicles (EVs) and hydrogen fuel cell vehicles (HFCVs) replace fossil-fueled transport, infrastructure demands for power generation, grid expansion, and manufacturing rise, along with material constraints and emissions. We present a multiscale modeling and optimization framework that links energy, materials, and mobility. The model incorporates life cycle assessment, EV charging strategies, energy storage, and carbon pricing to identify cost-effective, low-emission solutions. Applied to Texas, the framework explores fleet electrification scenarios under material availability, grid capacity, and policy constraints. Results reveal optimal configurations and technology pathways that balance cost, emissions, and infrastructure feasibility. This work supports industry and policy decisions at the intersection of vehicle electrification, energy systems, and sustainable supply chains.