2024 AIChE Annual Meeting

Session: Systems Biology: Cancer and Immunoengineering

This session covers systems biology approaches to study cancer and the immune systems, including how these systems interact with drug therapies and metabolism.

Co-Chairs

Presentations

03:30 PM

(595a) Invited Talk: Interpretable and Explainable Support Vector Machines: Applications in Cancer Therapeutic Design and Immunoengineering
Christopher Kieslich

04:10 PM

(595b) Uncontrolled Macropinocytosis Leading to Glioblastoma Cell Death Involves Disruptions to the Cytoskeletal Network.
Sarah Buchanan, Matthew Lazzara

04:28 PM

(595c) Evaluating the Role of Antibody-Drug Conjugate Immune System Effects and Payload Sensitivity in Low HER2+ Solid Tumors Via Agent-Based Modeling
Melissa Calopiz, Jennifer Linderman, Greg Thurber

04:46 PM

(595d) Ensemble Absolute Metabolite Quantitation in T Cells Reveals Conserved Features of Immunometabolism
Samantha O'Keeffe, Elle McCue, Harin Sim, Junyoung Park

05:04 PM

(595e) Evaluation of Cytosolic and Mitochondrial NADPH Dynamics Reveals Their Relative Contribution to Growth Rates in Cancer Cells
SUN Jin Moon, Anush Chiappino-Pepe, Wentao Dong, Joanne Kelleher, Matthew Vander Heiden, Gregory Stephanopoulos, Hadley D. Sikes

05:22 PM

(595f) Towards Cancer Digital Twins: Simulating Tumor Heterogeneity and Patient Response Using Tissue Level Agent-Based Modeling of Prostate Cancer
Sharvari Kemkar, Mengdi Tao, Alokendra Ghosh, Ravi Radhakrishnan

05:40 PM

(595g) Molecular Models Indicate Stronger Binding of HIV-1 to Co-Receptor CXCR4 Compared to CCR5 at a Viral Population Level
Bailey Zinger, Jonathan Faris, Kayla G. Sprenger