2024 AIChE Annual Meeting

Session: Pharma 4.0 (Advanced Controls, Process Automation, Data Analytics, etc.)

This session will discuss progress towards Pharma 4.0 through advancements in digitalization, process modeling, and process control. Contributions include the use of digital twins for control, optimization, and risk assessment; mechanistic and data-driven models; and establishing secure and FAIR digital infrastructures in industrial settings.

Chair

Co-Chair

Chowdhury, A., Process Systems Enterprise

Presentations

03:30 PM

(423a) State Estimation for Manufacturing of mRNA-Based Vaccines and Therapeutics: A Lyophilization Case Study
Srisuma, P., Barbastathis, G., Braatz, R.

03:51 PM

(423b) Advancing Solubility Prediction Using an AI-Driven Tool for Resource Optimization in Pharmaceutical Research
Pereira Diaz, L., Ramirez Galilea, A., Kukor, A., Nazemifard, N., Henson, M.

04:12 PM

(423c) Sequential, Simulation-Based Manufacturing Execution System for the Planning of Pharmaceutical Production
Casas, D., García-Muñoz, S.

04:33 PM

(423d) Digital Real-Time Release Testing in Continuous Tablet Manufacturing
Celikovic, S., Rehrl, J., Fraga, R. M., Steinberger, M., Horn, M., Khinast, J., Sacher, S., Kottlan, A.

04:54 PM

(423e) An Automated Crystallization-Filtration-Drying Workstation: Development and Application from the Perspective of Pharmaceutical Industry
Su, Q., Wijethunga, T., Willcox, D., Luciani, C.

05:15 PM

(423f) Development and Application of a MULTI-Component MODEL with Radially-Dependent Droplet Drying for Pharmaceutical Spray Drying
Harris, P., Jonuzaj, S., Bellinghausen, S., Li, X., Wong, L. H., Abdullahi, H., Patil, Y., Rose, J., Burcham, C. L.

05:36 PM

(423g) The Pursuit of Tighter Titer: Model Predictive Control of Monoclonal Antibody Titer Under Disturbances
Hatzenbeller, Z., Nikolakopoulou, A., Luo, Y.