2024 AIChE Annual Meeting

Session: Pharma 4.0 (Advanced Controls, Process Automation, Data Analytics, etc.)

This session will discuss progress towards Pharma 4.0 through advancements in digitalization, process modeling, and process control. Contributions include the use of digital twins for control, optimization, and risk assessment; mechanistic and data-driven models; and establishing secure and FAIR digital infrastructures in industrial settings.

Chair

Co-Chair

Ananya Chowdhury, Process Systems Enterprise

Presentations

03:30 PM

(423a) State Estimation for Manufacturing of mRNA-Based Vaccines and Therapeutics: A Lyophilization Case Study
Prakitr Srisuma, George Barbastathis, Richard Braatz

03:51 PM

(423b) Advancing Solubility Prediction Using an AI-Driven Tool for Resource Optimization in Pharmaceutical Research
Laura Pereira Diaz, Adrian Ramirez Galilea, Andrew Kukor, Neda Nazemifard, Mark Henson

04:12 PM

(423c) Sequential, Simulation-Based Manufacturing Execution System for the Planning of Pharmaceutical Production
Daniel Casas, Salvador García-Muñoz

04:33 PM

(423d) Digital Real-Time Release Testing in Continuous Tablet Manufacturing
Selma Celikovic, Jakob Rehrl, Ruben Martins Fraga, Martin Steinberger, Martin Horn, Johannes Khinast, Stephan Sacher, Andreas Kottlan

04:54 PM

(423e) An Automated Crystallization-Filtration-Drying Workstation: Development and Application from the Perspective of Pharmaceutical Industry
Qinglin Su, Tharanga Wijethunga, David Willcox, Carla Luciani

05:15 PM

(423f) Development and Application of a MULTI-Component MODEL with Radially-Dependent Droplet Drying for Pharmaceutical Spray Drying
Patrick Harris, Suela Jonuzaj, Stefan Bellinghausen, Xin Li, Lok Hang Wong, Hassan Abdullahi, Yogesh Patil, John Rose, Christopher L. Burcham

05:36 PM

(423g) The Pursuit of Tighter Titer: Model Predictive Control of Monoclonal Antibody Titer Under Disturbances
Zach Hatzenbeller, Anastasia Nikolakopoulou, Yu Luo