(548a) Shell Thomas Baron Award In Fluid-Particle Systems: Magnetic nanoparticle suspensions in time varying magnetic fields – colloidal hydrodynamics to biomedical applications

Magnetic nanoparticles respond to time varying magnetic fields via a combination of internal dipole and whole-particle rotation, depending on factors such as thermal motion, hydrodynamic drag, magnetic torques, and internal

barriers to dipole rotation. Depending on the amplitude and frequency of the time varying magnetic field, the nano-particle’s response can give rise to the conversion of magnetic field energy into heat or to a signal which can be used

to monitor nanoparticle rotational diffusion or quantify nanoparticle distribution in a subject. This multitude of magnetic responses, coupled with their biocompatibility, make iron oxide nanoparticles of great interest in sensing,

biomedical imaging, drug delivery, and thermal therapy. In this talk I will provide an overview of the theory of magnetic nanoparticle response to time varying magnetic fields and my group’s work advancing several of these

applications, including monitoring nanoparticle mobility in complex and biological fluids, cancer thermal therapy, rewarming of cryopreserved organs, and non-invasive, unambiguous, and quantitative tracking of nanoparticles and cells using magnetic particle imaging.