2023 AIChE Annual Meeting

Session: Scaling Up: Approaches for Streamlining Biomanufacturing Time to and Output of Product

Co-Chairs

Amol Janorkar, University of Mississippi Medical Center

Presentations

12:30 PM

(634a) Real-Time Modeling of the Growth and Phenotype of a Cytotoxic T Cell Line for Culture in a Novel Centrifugal Bioreactor with Applications in Immunotherapy
Brenden Fraser-Hevlin, Kitana Kaiphanliam, William C. Davis, Bernard Van Wie

12:48 PM

(634b) Development of Lateral Flow Assays for Rapid Quantification of Cell Culture Targets
Natalia Majewska Nepomuceno, Ravali Raju, Richard C. Willson, Katerina Kourentzi, Binh Vu, Vijay Maranholkar, Kristen Brosamer

01:06 PM

(634c) Leveraging Prior Knowledge and General Cell Culture Models to Configure and Validate Bioreactor Digital Twins across Scales and Cell Lines
Joana Saldida, Viktoria Gkoutzioupa, Alexandros Kiparissides, Sarah Fadda, Edward Close

01:24 PM

(634d) Therapeutic Protein Production Is Enhanced By Debottlenecking Secretion in Cells Stressed By Overproduction
Ryan Splichal, Christina Chan, S. Patrick Walton

01:42 PM

(634e) Application of Continuous Manufacturing to Upstream Cell Culture Process with Focus to Speed to Clinic
Roli Kargupta, Chelsea Phuangthong, Michael B. Deck, Nathaniel Ruppert, Karen (Min-yea) Lee, Tariq B. Atieh, Kyle Devenney, Rebecca A. Chmielowski, Venkata S. Tayi

02:00 PM

(634f) Engineered Biosynthesis of Benzoxazoles in Escherichia coli
Huanrong Ouyang

02:18 PM

(634g) Invited Talk: Developing Patient Focused Biologics Drug Product: Formulation, Process and Manufacturing Approaches
Parag Kolhe