2023 AIChE Annual Meeting

Session: Process models for drug substance, drug product, and biopharmaceuticals Part 2

Chair

Co-Chairs

Steven Ferguson, University College Dublin
Kakasaheb Nandiwale, Massachusetts Institute of Technology

Presentations

08:00 AM

(660a) A Pharmaceutical Application of the Process Systems Engineering Workflow: Combining Data-Driven Approaches with Physics-Based Models for Fluid Bed Granulation.
Salvador García-Muñoz

08:21 AM

(660b) Optimizing the Design of a Compaction Simulator Using Discrete Element Method (DEM)
Amir Esteghamatian, Jordan Arcangel, Daniel O. Blackwood

08:42 AM

(660c) Model Development and Experimental Validation for Predicting Drug Release in Bilayer Osmotic Tablets
Mahesh Tirumkudulu, Pankaj Doshi, Weili Yu, Bhawana Tomar, Sweta Manthena, Alfred Berchielli

09:03 AM

(660d) Water Activity As Indicator for Antibody Stability in Lyophilized Formulations
Maximilian Zäh, Christoph Brandenbusch, Gerhard Winter, Gabriele Sadowski

09:24 AM

(660e) Dynamics and Control of Oscillatory Bioreactors
Krystian Ganko, Pavan Inguva, Alexis B. Dubs, Richard Braatz

09:45 AM

(660f) Mechanistic Process Modeling of in Vitro Transcription to Enable RNA Production Platforms
Simon Daniel, Cleo Kontoravdi, Nilay Shah

10:06 AM

(660g) Modeling the Effect of Bioreactor pH on Chinese Hamster Ovary Cell Metabolism and Site-Specific N-Linked Glycosylation of VRC01 Mab
Jayanth Venkatarama Reddy, Eleftherios Papoutsakis, Marianthi Ierapetritou