2023 AIChE Annual Meeting

Session: Poster session: Bioengineering

Chair

Jamie Spangler, Johns Hopkins University

Co-Chairs

Yongchan Kwon, Louisiana State University
Christopher Kieslich, Auburn University
Jason Boock, Miami University (OH)
Phanourios Tamamis, Texas A&M University

Presentations

03:30 PM

(27a) Photoenzymatic Asymmetric Hydroamination of Simple Aliphatic Amines and Vinyl Arene Olefins
Wesley Harrison, Huimin Zhao
(27bf) Engineering High-Throughput Fluorescent Reporters for Selenocysteine Incorporation
Devon Kulhanek, Zach Jansen, Qiyao Wei, Andrew Gilmour, Ross Thyer
(27cj) Constraining the Predictions of Conserved SMAD Signaling Pathway through Parameter Identifiability Informed Experimental Design.
Razeen Shaikh, Gregory Reeves
(27r) Enhanced Protein Stability Enabled By Mixtures of Ionic and Amphoteric Surfactants Compared to Each Alone
Jason Boock, Jason Berberich, Evan Danielson, Kerri Peterson, Kayla Thompson, Elaine Reece, Tridwip Sen
(27al) Programmable RNA Detection with CRISPR-Cas12a
Santosh R. Rananaware, Grace Shoemaker, Katelyn Meister, Emma K. Vesco, Swapnil Anekar, Luke Samuel W. Sandoval, Nicolas C. Macaluso, Long Nguyen, Piyush Jain
(27ay) Engineering Corynebacterium Glutamicum for Biomanufacturing of ?-Ketoadipate from Lignin-Derived Aromatics
Arren Liu, Tyler Okane, Nandini Kannoju, David Nielsen, Arul Mozhy Varman
(27ck) Using Experimentally Validated ML Models to Predict the Thawing Time of Biologics during Large Scale Freeze-Thawing Cycles
Venkatraman Nagarajan, Bodhisattwa Chaudhuri, Tibo Duran, Tanu Mehta, Bruna Minatovicz, Lauren Fontana, Yi Wang, Yangchao Luo
(27bq) Engineered Biological Security Systems: Introducing Biotic Cryptography and Encryption
Dowan Kim, Corey Wilson, Ishita Kumar
(27bd) Harnessing Robustness of Thermophilic Bacillus Coagulans for Conversion of Switchgrass Hydrolysates to Designer Bioesters at Elevated Temperatures
David Dooley, Seunghyun Ryu, Bruce S. Dien, Cong Trinh, Jackson Edwards, Khanh Ha, Richard Giannone
(27ak) Multiplexing of Cas Orthologs for Disease Detection
Briana L.M. Pizzano, Piyush Jain, Lilia G. Yang, Santosh R. Rananaware, Anne Fang, Sydney G. Antal, Zoe R. Fang, Long T. Nguyen, Noah R. Rakestraw, Victor Vargas
(27ba) Continuous Production of Acetic Acid By Eubacterium Limosum KIST612 Using an External Membrane Module
Gwonwoo Park, Myounghoon Moon, Min-Sik Kim
(27an) Nanopore Sequencing of 8-Letter Xenonucleic Acids
Hinako Kawabe, Jorge A. Marchand
(27aa) Directed Evolution of an Alpha-Synuclein Degrading Enzyme
Carl Denard, Lawton Long, Cassidy Simas
(27av) PAM-Independent Detection of Nucleic Acid Targets with CRISPR-Cas12a
Santosh Rananaware, Katelyn Meister, Grace Shoemaker, Luke Samuel W. Sandoval, Emma K. Vesco, Jordan Lewis, Briana Pizzano, Piyush Jain
(27bm) Dynamic DNA Nanoaggregation Driven By Ionic Self-Association
Kevin Lin, Sneha Mukherjee, Albert J. Keung, Orlin D. Velev
(27bk) Investigating the Relaxase Behavior and Replication Functionality of the Mobilization Protein Mobv in the Plasmid pBBR1
Mark Kathol, Cheryl Immethun, Dianna Morris, Rajib Saha
(27bb) Enzymatic Optimization of the Biosynthetic Production of Paraxanthine By Site-Saturated Mutagenesis with Enhanced Formaldehyde-Sensitive Selection
Meredith Mock, Margaret Kapperman, Camden Hutchison, Joseph Rodriguez, Kayla Pakulski, Nick Gleason, Ryan Summers
(27am) An Ultrasensitive Amplification-Free Nucleic Acid Detection Using CRISPR Chain Reaction v2
Minji Chang, Piyush Jain, Santosh Rananaware, Carlos Orosco, Emma K. Vesco, Grace Shoemaker, Lilia Yang
(27ad) 8-Oxo-7,8-Dihydroguanosine Alters RNA Degradation Behavior of Polynucleotide Phosphorylase
Lucas Miller, Shawn Schowe, Runhua Han, Vashita Jain, Sean Engels, Juan Camilo Gonzalez Rivera, Marino Resendiz, Lydia Contreras
(27ah) In Situ Characterization of Ammonia-Dependent Enzymes
Adam Caparco, Bettina Bommarius, Carine Vergne-Vaxelaire, Julie Champion, Andreas Bommarius, Laurine Ducrot
(27ao) Dielectric Characterization of Babesia Bovis Using the Crossover Frequency Technique on a Point and Planar Electrodes Microfluidic Device
Soumya K. Srivastava, Raphael Oladokun
(27aw) Production and Application of SARS-CoV-2 Pseudotyped Virus for Screening Antiviral Efficacy of Test Compounds on a High-Throughput Platform
Maisha Feroz, Seok-Joon Kwon, Jonathan Dordick, Yuefan Song
(27cl) Balancing Monoatomic Ion-Biomolecular Interactions in the Polarizable Drude Force Field
Yiling Nan, Alexander D. MacKerell
(27q) Probing the Origins of Collateral Fitness Effects? of Mutations
Cameron Goff, Marc Ostermeier
(27ae) Environmental Dependence of Collateral Fitness Effects
Erh-Yeh Tsou, Jacob D. Mehlhoff, Jacob D. Mehlhoff, Marc Ostermeier
(27ci) Multi-Omic Characterization of CHO Cells Reveals Fluxomic Diversity and Amino Acid Utilization Bottlenecks in High-producer Clones
Saratram Gopalakrishnan, William Johnson, Miguel Angel Valderrama-Gomez, Elcin Icten, Cleo Kontoravdi, Nathan Lewis
(27t) Comparison of GST and SUMO Fusion Tags for Enhanced Yield and Purity of Recombinant Osh4
Dinara Konakbayeva, Andrew Loveland, Jeffery Klauda, Amy Karlsson
(27bs) Glutathione-Responsive Disulfide-Containing Poly (?-amino esters) Nanogels for Drug Delivery Applications
Anastasiia Aronova, Thomas D. Dziubla, Alea Smith, Brittany Givens Rassoolkhani
(27u) Understanding the Inherent Bias in the Activity of Mismatch Specific Exonuclease
Qing Sun, Rushant Sabnis
(27ch) A Novel Method to Measure Transcriptional Maturity of Engineered Liver Cells
Daniel Guiggey, Natesh Parashurama
(27bj) Heterologous Derived Proteins Tethered to the Surface of Yeast: Arming Saccharomyces Cerevisiae with Sars-Cov-2 Receptor Binding Domain and Green Fluorescent Protein.
Shadrach Ibinola, Hazim Aljewari, Sebastian Freeman, Vicki Thompson, Kaiming Ye, Robert Beitle
(27d) Polyethylene Terephthalate (PET) Plastic Intermediates Deconstruction in One Pot B. Subtilis Bioprocess
Arul Mozhy Varman, Bethany Kalsheur, Haley McKeown, Apurv Mhatre, Bruce Rittmann
(27cd) Analysis of Pmad and Medea Expression in BMP Pathway in S2 Cells and Drosophila Germline Stem Cells Niche
Hung-Yuan Chen, Gregory Reeves
(27bn) Engineering of Tunable Cell Network with Endogenous Template Activation of Non-Excitable Cells
Junkai Xie, Bo-Chuan Huang, Chongli Yuan
(27m) Bioreactors Scale-up and Optimization from Lab to Manufacturing Scale
Nima Yazdanpanah
(27ac) Meta-Analysis of Proteolytic Cleavage Specificity Using Machine Learning
Suhyeon Kim, Hyeju Song, Sumaiya Islam, Christopher Kieslich
(27s) Adaptability of 22 Functional Cas12a Orthologs Using a Combinatorial Approach for Nucleic Acid Detection in Clinical Samples
Dylan Carman, Noah Rakestraw, Nicolas C. Macaluso, Long Nguyen, Piyush Jain
(27at) A Rapid, Fully Automated Modular Electrochemical Platform Based on a Porous Flow-through Electrode for Sensing Biological Molecules of Interest
Sagnik Basuray, Yu-Hsuan Cheng, Zhenglong Li, Sreerag Kaaliveetil, Niranjan Haridas
(27ax) Nonfluorescent Ratiometric Sensing Utilizing CRISPR-Cas12a-Induced DNA Supercoil Relaxation
Noor Mohammad, Logan Talton, Selen Dalgan, Qingshan Wei
(27cg) An SPNS1-Dependent Lysosomal Lipid Transport Pathway That Enables Cell Survival Under Choline Limitation
Wentao Dong, Samantha Scharenberg, Ali Ghoochani, Kwamina Nyame, Roni Levin-Konigsberg, Aswini Krishnan, Eshaan Rawat, Kaitlyn Spees, Michael Bassik, Monther Abu-Remaileh
(27bg) Feedforward Loop-Based Antithetic Controller for Improved Adaptation Dynamics
Thales Spartalis, Xun Tang
(27bo) Assemblytron: Flexible Automation of DNA Assembly with Opentrons OT-2 Lab Robots
John Bryant, Clay Wright, Mason Kellinger, Cameron Longmire, Ryan Miller
(27bx) Illuminating Cell Entry Pathways of Sars-Cov-2 By Replicating Distinct Host Environments on a Bioelectronic Sensor
Susan Daniel, Zhongmou Chao, Ekaterina Selivanovitch, Konstantinos Kallitsis, Zixuan Lu, Alberto Salleo, Roisin Owens
(27g) Polymer Motion Energizing Enzyme Conformational Dynamics and Catalytic Kinetics in Organic Solvents
Yupei Jian, Zheng Liu
(27ag) Discovery and Characterization of a Structurally Unique Heterocyclic Peptide Enterolysin S
Chengyou Shi, Huimin Zhao, Marko Nesic, David Sarlah
(27aj) Artificial Lipid Biomembranes for Full-Length Sars-Cov-2 Receptor
Ting Wang
(27w) Metabolic Engineered Escherichia coli Strains to Express Flavoprotein Monooxygenases from Actinomycetes Isolated from the Atacama Desert for Industrial Applications.
Irene Martinez, Carolina Gonzalez
(27be) Agent-Based Metabolic Modeling for the Rational Engineering of Chlamydomonas Reinhardtii
Sandra Gomez Romero, Nanette Boyle
(27v) Engineering Bispecific Receptor Decoy Antagonists to Treat Neovascular Eye Diseases
Paul Sargunas, Emily Ariail, Jamie Spangler
(27cb) Development of a Genome-Scale Metabolic Model for Auxenochlorella Protothecoides to Enable Rational Engineering
Mark Vigliotti, Jacob Tamburro, Nanette Boyle