2023 AIChE Annual Meeting

Session: Mixing Scale-Up and Scale-Down Issues in Pharmaceutical & Biopharmaceutical Processes

Chair

Matthew Flamm, Merck & Co., Inc.

Co-Chair

Luis Sierra, Merck & Co., Inc.

Presentations

08:00 AM

(456a) CFD Simulation of Impulse Mixers
John Thomas, Iman Mirzaee, Johannes Wutz, Masoud Ahmadi, Saeed Jafari Kang, Shahab Golshan, Fabrice Schlegel, Pablo A. Rolandi

08:30 AM

(456b) Scale up/Scale Down of Impulse Mixer Using CFD
Hossam Metwally, Chadakarn Sirasitthichoke, Robert Blizzard, Mustafa Kaddoura, Kringan Saha

09:00 AM

(456c) Mixing Time and Fluid Flow Profiles in Asymmetric Flow Jet Mixing Reactors
Jessica Winter, Faiz Khan, David Mualen, Barbara E. Wyslouzil, Nicholas Brunelli

09:30 AM

(456d) The Importance of Selecting Appropriate Scale-up Concepts: One Example of Mixing Issues in an Industrial Fermentation Process
Sören Bernauer

10:00 AM

(456e) Methodology for Mixing Scale-up: Safety, Quality & Reliability
Michael Hamlin, Ankur Kapil