2023 AIChE Annual Meeting

Session: Crystallization Case Studies from Industry

Chair

Lotfi Derdour, Glaxosmithkline

Co-Chairs

Presentations

12:33 PM

(302a) Developing and Optimizing a Quench-Crystallization Operation in Drug Substance Manufacturing
James Fostinis, Daniel Griffin, Liang Zhang, Andrew Parsons

12:53 PM

(302b) Control of Crystallization Process and Crystal Form of Pharmaceutical Intermediates
Zhe Li, Boris Shekunov, Sze Wing Wong

01:13 PM

(302c) A Novel Approach to Achieve Clarifying Filtration for Poorly Soluble Organic Compounds and to Improve Polymorphic Control during Reactive Crystallization
Lotfi Derdour

01:33 PM

(302d) Complex Oiling-out Behavior with Stable and Metastable Liquid Phases: Implications for Pharmaceutical Development
Da Hye Yang, Francesco Ricci, Fredrik Nordstrom, Na Li

02:00 PM

(302e) Development of a Thermodynamic Crystallization Using Data Rich Experimentation (DRE)
David Lamberto

02:20 PM

(302f) Determining Critical Water Activity Mediated Conversion of Anhydrate-Hydrate Solid Forms
Joseph Kalkowski, Francheska M. Reyes Figueroa, Giovanni López Burgos, Deliang Zhou, Geoff G. Z. Zhang

02:40 PM

(173a) Implementation of Continuous Crystallization As a Processing Method for Robust Control of API Purity and Crystal Form
Gary Morris, Aaron P. Keogh, Umar Farid, Andreas Stumpf