2023 AIChE Annual Meeting

Session: Control Strategies for Biopharmaceutical and Pharmaceutical Process Design and Development

Chair

Co-Chair

Bei Chen, AbbVie

Presentations

08:00 AM

(563a) Sublimation Front Shape during Pharmaceutical Lyophilization: Investigation By Simulation
Isaac Wheeler, Vivek Narsimhan, Alina Alexeenko

08:21 AM

(543a) Development and De-Risking of a Green, Drug Substance Intermediate Process Using Data-Rich Experimentation
Zachary Brentzel, David Stephens

08:42 AM

(563b) Understanding Adsorption Behavior of Polysorbate-20 to Sterile Filters in Antibody Drug Substance Final Filtration Process
Jian Ren, Yun Zhang, Chen Wang

09:03 AM

(563c) Optimization of Glucose Feeding Strategies of Fed-Batch Bioreactors for Monoclonal Antibody Production
Anastasia Nikolakopoulou, Ou Yang, Gabriele Bano

09:24 AM

(563d) Towards Quality Control of Biotherapeutic Products through Soft Sensing of Intracellular States
Luxi Yu, Ehecatl Antonio del Rio Chanona, Cleo Kontoravdi

09:45 AM

(583h) Automated Bioreactor Feedback Control Via Mast-Nova-Deltav Integration
Chris Lowe, Zach Houle, Leo Karmiy, Mihir Dhamal, Rachel Harmon

10:06 AM

(563f) Why Thermal Interactions Among Vials Matter in Pharmaceutical Freeze-Drying: Experimental Evidence and Mechanistic Modeling
Leif-Thore Deck, Andraž Košir, Nicole Ferru, Marco Mazzotti