2023 AIChE Annual Meeting

Session: Continuous Processing in Drug Substance

Chair

Rogers, L., On Demand Pharmaceuticals

Co-Chairs

Gerogiorgis, D., University of Edinburgh
Griffin, D., Amgen Inc.

Presentations

03:30 PM

(613a) Recent Progress in Heterogeneous Hydrogenations Using an Automated Flow Platform Equipped with PAT
Hone, C., Kappe, C. O.

03:51 PM

(613b) Applying Feedback Control to Enhance Continuous Processing in Drug Substance Manufacturing
Dobson, B., Wyvratt, B. M., McMullen, J., Fine, A., Neel, A., Lévesque, F., Spencer, G., Tucci, W., Nappi, J., Burd, S., Delello, J., Lin, Z., Ji Chen, Y., Xue, M.

04:12 PM

(613c) Development of a Cryogenic Flow Synthesis and Continuous Extraction Process with Enhanced Yield, Process Control, and Greenness.
Jonuzaj, S., Reizman, B., Kaczorowski, N., Miller, R. D., Day, J., Vaidyaraman, S., Veltri, L., Held, C. B., Burcham, C., Cole, K. P.

04:33 PM

(613d) Accelerated Reaction Development with Automated Transient Flow Experiments
Nambiar, A. M. K.

04:54 PM

(613e) Process Modeling, Simulation and Technoeconomic Evaluation of Batch Vs. Continuous Pharmaceutical Manufacturing (CPM) of Cephalexin
Blair, M., Gerogiorgis, D., Tzanakopoulou, V. E., Jones, W.

05:15 PM

(613f) Continuous Cryogenic Flow Amination and Centrifugal Extraction - Scale-up and Processing Strategy in Multi-Kilo Scale.
Dhanraj, D., Featherston, A. L.

05:36 PM

(613g) A Modular Continuous Manufacturing Platform for Fine Chemicals Via Lithium-Halogen Exchange and Electrophilic Substitution
Campbell, K., Nagy, K., Ford, D. D., Fang, Y. Q., Hasan, A., Hurlow, E., Caporello, M., Un, A.