2023 AIChE Annual Meeting

Session: Continuous Processing in Drug Substance

Chair

Luke Rogers, On Demand Pharmaceuticals

Co-Chairs

Dimitrios Gerogiorgis, University of Edinburgh
Daniel Griffin, Amgen Inc.

Presentations

03:30 PM

(613a) Recent Progress in Heterogeneous Hydrogenations Using an Automated Flow Platform Equipped with PAT
Christopher Hone, C. Oliver Kappe

03:51 PM

(613b) Applying Feedback Control to Enhance Continuous Processing in Drug Substance Manufacturing
Brittany Dobson, Brian M. Wyvratt, Jonathan McMullen, Adam Fine, Andrew Neel, François Lévesque, Glenn Spencer, William Tucci, Jarod Nappi, Steven Burd, John Delello, Zhihao Lin, Yining Ji Chen, Meng Xue

04:12 PM

(613c) Development of a Cryogenic Flow Synthesis and Continuous Extraction Process with Enhanced Yield, Process Control, and Greenness.
Suela Jonuzaj, Brandon Reizman, Nick Kaczorowski, Richard D. Miller, Jon Day, Shankar Vaidyaraman, Lindsay Veltri, Charles B. Held, Christopher Burcham, Kevin P. Cole

04:33 PM

(613d) Accelerated Reaction Development with Automated Transient Flow Experiments
Anirudh M.K. Nambiar

04:54 PM

(613e) Process Modeling, Simulation and Technoeconomic Evaluation of Batch Vs. Continuous Pharmaceutical Manufacturing (CPM) of Cephalexin
Matthew Blair, Dimitrios Gerogiorgis, Vasiliki E. Tzanakopoulou, Wil Jones

05:15 PM

(613f) Continuous Cryogenic Flow Amination and Centrifugal Extraction - Scale-up and Processing Strategy in Multi-Kilo Scale.
David Dhanraj, Aaron L Featherston

05:36 PM

(613g) A Modular Continuous Manufacturing Platform for Fine Chemicals Via Lithium-Halogen Exchange and Electrophilic Substitution
Kiersten Campbell, Kevin Nagy, David D. Ford, Yuan-Qing Fang, Ali Hasan, Evan Hurlow, Michaella Caporello, Andy Un