2023 AIChE Annual Meeting

Session: Advances in Process Development for Formulation and Pharmaceutical Applications Using Automation and PATs

Chair

Co-Chair

Will Kowalchyk, METTLER TOLEDO

Presentations

03:30 PM

(583a) Impact of Rheology and Process Variables on the Development and Scale-up of a Drum Filling Process for Dry Powder Inhalers
Rui Churro, João Pires, Carolina Lopes, Susana Saldanha, Maria Inês Lopes

03:51 PM

(583b) Laser Speckle Probe for Monitoring Pharmaceutical Drying
Ajinkya Pandit, Qihang Zhang, Moo Sun Hong, Wenlong Tang, Charles D. Papageorgiou, Neda Nazemifard, Yihui Yang, Michael Schwaerzler, Tolutola Oyetunde, Christopher Mitchell, Richard D. Braatz, George Barbastathis, Allan S. Myerson

04:12 PM

(583c) Understanding of Polymorphic Phase Transformation of Artemisinin in Polymer-Based Formulation
Suresh Manivel, Torsten Stelzer

04:33 PM

(583d) Droplet to Particle Model Prediction By Coupling Solution Rheological Characterization, CFD and Phase Doppler Analysis
Marcia Tavares, Pedro Monteiro, Clara Sá Couto

04:54 PM

(583f) Considerations for Biocatalytic Oxidation Development of a Key Intermediate for a Drug Candidate
Michelle Zheng, Shorouk Badir, Ajit Vikram, Michael Whittington, Yangzhong Qin, Yining Ji Chen, Keith A. Mattern, Anna Dunn, Birgit Kosjek, David Vargas, Nastaran Salehi Marzijarani, James P. Corry

05:15 PM

(583g) Development of a Continuous Inline Monitored Lab Plant Based on the Microfluidizer® Technology for the Production of Nanoparticles
Christina Glader, Ramona Jeitler, Carolin Tetyczka, Yan Wang, Manuel Zettl, Johannes G. Khinast, Manon Rossano, Steve Mesite, Matthias Luebbert, Eva Roblegg, Lisa Kuchler

05:36 PM

(583e) Near-Infrared Spectroscopy As a PAT Tool for Monitoring and Controlling Active Pharmaceutical Ingredient Crystallinity in High-Risk Drug-Product Manufacturing
Sonal Mazumder, Samuel R. Henson