2023 AIChE Annual Meeting

Session: Advances in Novel Pharmaceutical Process Design, Development, and Control using Data-Rich Experiments and/or Models

Chair

Co-Chair

Bei Chen, AbbVie

Presentations

12:30 PM

(543b) Process Development and Characterization for Impurity Control of a Dynamic Kinetic Resolution Reaction Using Data Rich Experimentation
Sean Dubina, Scott McCann, Thu Vi, Victor Schultz, Nilusha Padivitage, Daniel DiRocco, Jonathan McMullen

12:51 PM

(543c) Coordinated API and Formulation Development Strategy Utilizing API Attribute Range Studies with Line of Sight to Commercial Process Nominations
Thomas Kwok, Clara Hartmanshenn, Steve Crowley, Alex Bechtold, Alex Confer, Jeff Mora, Nate Contrella, Lorenzo Codan, David Lamberto, Jerry Klinzing, Melanie Marota

01:12 PM

(543d) Novel Concepts for Processing and Automation of Pharmaceutical End-to-End Manufacturing
Lisa Kuchler, Jason Williams, Jakob Rehrl, Stefano Martinuzzi, Markus Tranninger, Johannes Poms, Martin Sipek, Ella Hofreiter, Dirk Kirschneck, Martin Horn, Johannes G. Khinast, Stephan Sacher

01:33 PM

(543e) Advanced Process Control Design for a Continuous API Synthesis Process
Nima Yazdanpanah

01:54 PM

(543f) Development and Scale-up of a Robust Two Step Telescope Reaction and Crystallization Via High-Throughput Experimentation and in-Line Process Monitoring
Kelvin Jones, Maryll Geherty, Lucas Hernandez, Bahar Inankur, Scott Savage, Christopher Wilbert

02:15 PM

(543g) Accelerating Drug Development with Suntheticsml: Removing Barriers for Machine Learning Adoption in Reaction Optimization
César Urbina-Blanco, Daniela Blanco

02:36 PM

(543h) Optimizing Carbon Treatment Methods for Successful Scale-up
Arnav Malkani, Carmen Chen, Kaitlyn Brinza, Hong Li, David Schenk, Kevin Sirk, Adam Fine, Jonathan McMullen