2023 AIChE Annual Meeting

Session: Advances in New Modalities: Discovery and Production

Chair

Zhu, X., Amgen Inc

Co-Chairs

Lowe, C., University of Massachusetts-Amherst
Gu, Q., Carnegie Mellon University

Presentations

08:00 AM

(485a) Scalable One-Pot Liquid Phase Oligonucleotide Synthesis Enhanced By Organic Solvent Nanofiltration
Kelly, R., Parga, C., Ferguson, S.

08:20 AM

(485b) Mechanistic Modeling to Enhance Production of Recombinant Adeno-Associated Virus with Insect Cells
Joseph, J., Destro, F., Srinivasan, P., Braatz, R. D., Kotin, R., Cecchini, S., Kanter, J., Neufeld, C., Wolfrum, J. M., Barone, P. W., Springs, S., Sinskey, A.

08:40 AM

(485c) Development of Solid Phase Peptide Synthesis Kinetic Models for Impurity Control Strategies
Wang, J., Berglund, M., Buser, J. Y., Embry, M. C., Groh, J. M., Kopach, M., McFarland, A. D., Seibert, K., Viswanath, S.

09:00 AM

(485d) Mechanistic Modeling, Optimization, and Control of in-Vitro Transcription for mRNA Production
Stover, N. M., Ganko, K., Braatz, R.

09:30 AM

(485e) Coarse-Grained Molecular Dynamics Simulations of Adsorption of Adeno-Associated Virus Onto Ion-Exchange Chromatographic Media
Duran, T., Naik, S., Chanda, A., DiLuzio, W., Chaudhuri, B., Kneski, J.

09:50 AM

(485g) Robust Biomanufacturing of Recombinant AAV for Cardiac-Specific Gene Delivery
Kim, S., Chen, K., Liu, X., Zhou, L.

10:10 AM

(485h) Mab-Exo-AAV-Mediated Targeted Gene Therapy to Treat Triple-Negative Breast Cancer
Varadkar, T., Liu, X., Zhou, L., Zhou, Z., Chen, K., Zhang, J.