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Proceedings
2022 Annual Meeting
Pharmaceutical Discovery, Development and Manufacturing Forum
Predictive Scale-Up/Scale-Down for Production of Pharmaceuticals and Biopharmaceuticals II
2022 Annual Meeting
Session: Predictive Scale-Up/Scale-Down for Production of Pharmaceuticals and Biopharmaceuticals II
Chair
Manjrekar, O.
, AbbVie Inc.
Co-Chairs
Vecchiarello, N.
, Amgen
Eccles, M.
Presentations
08:00 AM
(82a) Implementation of a Small-Scale Capillary Shear Model to Facilitate Process Development of Disc Stack Centrifugation during the Harvest of Biopharmaceuticals
Frey, S.
,
Liao, J.
,
Koshari, S. H. S.
,
Luo, R.
,
Ubiera, A.
08:21 AM
(82b) Using Particle Size Distributions to Predict the Filterability of Materials throughout the Processing of Monoclonal Antibodies
Frey, S.
,
Zhang, H.
,
Luo, R.
,
Ubiera, A.
08:42 AM
(82c) Predictive CFD Mixing Model for Scale up/Down of Large Molecule Dug Product Formulation
Flamm, M.
,
Rizzo, J.
,
Seybold, H.
,
Mascaro, T.
,
Sarkar, A.
,
Modi, S.
,
Amato, C.
,
Ikeda, C.
09:03 AM
(82d) Model Aided Scale-up of Spray Drying for a Sticky API (low Glass Transition Temperature)
Kapil, A.
,
Hamlin, M.
,
Wombell, C.
,
Liu, L.
09:24 AM
(82e) In silico Modeling of Roller Compaction Processes for Scale-up and Tech Transfer: One Step Closer to Digital Twins
Rolandi, P. A.
,
Schlegel, F.
,
Alvarez-Nunez, F.
,
Chung, J.
,
Hamedi Rad, M.
,
Gour, S.
,
Daftardar, S.
,
Nguyen, D.
,
Perez-Aguilar, D.
,
Shen, D.
,
Chowdhury, A.
,
Icten Gencer, E.
,
Maritato, M.
,
Sengupta, R.
,
Ryan, K.
09:45 AM
(82f) Optimizing the Design and Scale-up of Agitated Filter Dryer
Turezo, G.
,
Nallamothu, S.
,
Kadam, M.
,
Haidari, A.
10:06 AM
(82g) Scalability and Predictability of Terminal Wet Milling Processes
Luciani, C.
,
Eccles, M.
,
Filios, M.