2022 Annual Meeting

Session: Mixing Scale-Up and Scale-Down Issues in Pharmaceutical Processes

Chair

Sierra, L., Merck & Co., Inc.

Co-Chair

Sirasitthichoke, C., New Jersey Institute of Technology

Presentations

08:00 AM

(459f) The challenges of detailed CFDsimulations ofstirred lab-scalebioreactors

08:30 AM

(459b) Using CFD to Predict Mixing Coefficients for Scale up

09:00 AM

(459c) A Design of Experiment (DOE)-Based Approach for Bioreactor Scale up and Cell Metabolic Reactions

09:30 AM

(459d) Scale-Down of Viral Inactivation Step: Principles and Practical Challenges

10:00 AM

(459e) Application of Gas-Liquid Mass Transfer Coefficient Fitting Techniques in Batch Reactors for Scale-up