2022 Annual Meeting

Session: Integrated Product and Process Design with Pharmaceutical Applications II

Chair

Pablo A. Rolandi, Amgen Inc.

Co-Chair

Qinglin Su, CONTINUUS Pharmaceutical

Presentations

03:30 PM

(411a) Plug-and-Play Software for Mechanistic Modelling of End-to-End Continuous Manufacturing of Monoclonal Antibodies
Moo Sun Hong, Amos E. Lu, Richard D. Braatz

03:51 PM

(411b) An Optimization-Based Approach to Identify Thermodynamically Stable Blends for Spray Drying Dispersions
Suela Jonuzaj, Malak Wehbe, Christopher Burcham, Amparo Galindo, George Jackson, Claire Adjiman

04:12 PM

(411c) Impact of Excipient Properties & Blending Process Parameter on Blend Uniformity of a Blend Prepared in Small Batches Semicontinuously Using Integrated Feeder-Blender System
Sumit Kumar, Gintaras V. Reklaitis, Zoltan Nagy, Marcial Gonzalez, Paul R. Mort

04:33 PM

(411d) Molecular Dynamics Modeling Based Investigation of the Effect of Freezing Rate on Protein Stability
Tibo Duran, Bruna Minatovicz, Ryan Bellucci, Jun Bai, Bodhisattwa Chaudhuri

04:54 PM

(411e) A Multi-Scale Approach to Understanding Spray Dried Dispersion Impurity Generation
James Miesle, Salvador Salvador Garcia, Matthew Walworth, Jason Melnick, Lars Magnusson, Alana Kurz, Kerri Fischer

05:15 PM

(411f) Parallel Process Development and Enzyme Evolution for Drug Substance Manufacturing
Sean Dubina, Scott McCann, Birgit Kosjek, Stephanie Chun, Nilusha Padivitage, Daniel DiRocco, Jonathan McMullen

05:36 PM

(411g) An Industrial in silico Modeling Platform for Reliable, Efficient, and Agile Process & Product Development
Fabrice Schlegel, Pablo A. Rolandi, Iman Mirzaee, Maxwell Maritato, Saman Seifi, Miguel Angel Valderrama-Gomez, Joao De Faria, Saeed Jafari Kang, Maryam Medghalchi, Justin Porth, Elcin Icten Gencer