2022 Annual Meeting

Session: Computational, Structure, Biophysical Protein Engineering

Chair

Daniel Woldring, Michigan State University

Co-Chair

Robert Pantazes, Auburn University

Presentations

12:30 PM

(314a) Beginning with the End in Mind: Integrating Cell-Free Protein Synthesis with Coarse-Grained Simulation for Site-Specific Optimization of Protein Therapeutic Pegylation.
Brad Bundy, Emily Zhao, Mehran Soltani, Addison K. Smith, J Porter Hunt, Joshua W. Wilkerson, Thomas Knotts

12:48 PM

(314b) Structural Characterization of an Effector-Biasing Interleukin-2 Immunocytokine
Joseph Gould, Elissa Leonard, Jamie Spangler

01:06 PM

(314c) Novel Experimental and Computational Approaches for Conformational Antibody Engineering
Matthew Smith, Alec Desai, Jennifer Zupancic, Peter Tessier

01:24 PM

(314d) Antibody Affinity and Specificity Co-Optimization Via Machine Learning
Patrick Kinnunen, Emily K. Makowski, Jennifer J. Linderman, Peter Tessier, Jie Huang, Lina Wu

01:42 PM

(314e) Combining Protein Sequence and Structure Pretraining
Hugh Yeh, Kevin Yang

02:00 PM

(314f) Computational Modeling of Sars-Cov-2 Spike RBD Binding to Human ACE2 Receptor Using Molecular Simulations and Machine Learning
Veda Sheersh Boorla, Chen Chen, Ratul Chowdhury, Deepro Banerjee, Victoria S Cavener, Ruth H Nissly, Abhinay Gontu, Nina R Boyle, Shubhada K Chothe, Lindsey LaBella, Padmaja Jakka, Santhamani Ramasamy, Kurt J Vandegrift, Meera Surendran Nair, Suresh V Kuchipudi, Costas D. Maranas

02:18 PM

(314g) Exploring the Features of Protein-Protein Interfaces to Enable Protein Design for Chemical Engineering
Robert Pantazes