2022 Annual Meeting

Session: Advances in New Modalities: Predictive Modeling Technologies

Chair

Xiaoxiang Zhu, Amgen Inc

Co-Chair

Moiz Diwan, Abbvie Inc.

Presentations

12:30 PM

(513a) Integrated Model-Based Design and Scale-up for Peptide Chromatographic Purification
Bhoja Kandela, Bent Colin, Shekhar Viswanath

12:51 PM

(513b) Model-Aided Reaction Kinetics and Rheology Study of Solid Phase Peptide Cleavage Process
Shekhar Viswanath, Jingyao Wang, Lexie Niemoeller, Yu Lu, Michael Kobierski, Bradley M. Campbell

01:33 PM

(513d) Coarse-Grained Molecular Dynamics Simulation of Aggregation and Surface Adsorption of ssDNA Loaded Adeno-Associated Viral Capsids
Tibo Duran, Arani Chanda, Willow DiLuzio, Ryan Bellucci, Shivangi Naik, Bodhisattwa Chaudhuri

01:54 PM

(513e) Leveraging Molecular Modeling in the Selection of Protein-Drug Candidates for Late-Stage Developability
Marco Blanco, Francis Insaidoo, Jainik Panchal, Veronica Juan, Marc Bailly

02:15 PM

(513f) Design of Experiments Compared to Artificial Neural Network Approach – How Can We Use Them to Understand Spray Drying of Biologics?
Elisabeth Fink, Daniela Fiedler, Isabella Aigner, Eva Roblegg, Johannes G. Khinast

02:36 PM

(513g) Investigating Fundamental Motions to Rapidly Predict Lyophilized Protein Stability
Andy Bommarius, Marcus T Cicerone, Kelly Badilla