2021 Annual Meeting

Session: Reaction Engineering in Pharmaceuticals and Fine Chemicals

Chair

Giri, G., University of Virginia

Co-Chair

Manjrekar, O., AbbVie Inc.

Presentations

08:00 AM

(446a) Continuous Ligand-Free Suzuki-Miyaura Cross-Coupling Reactions in a Packed Bed Flow Reactor Using an Easily Synthesized Siloxane Network-Supported Palladium Catalyst
Davis, B., Abolhasani, M., Bennett, J.

08:18 AM

(446b) Engineering Composite Hollow Fiber As a Heterogeneous Catalyst and Continuous-Flow Microfluidic Reactor for Sustainable Production of Fine Chemicals
Rownaghi, A.

08:36 AM

(446c) Development and Validation of Enzymatic Kinetic Model for the Synthesis of Cephalexin and Amoxicillin By Penicillin G Acylase at High Substrate and Product Concentrations
Harris, P., Rousseau, R., Grover, M., Bommarius, A.

08:54 AM

(446e) Optimizing Multistep Continuous Flow Organic Synthesis with Bayesian Optimization and Robotics
Nambiar, A. M. K., Breen, C. P., Hart, T., Jamison, T., Jensen, K., Kulesza, T.

09:12 AM

(446f) A Process Monitoring Approach for Multistep Continuous Flow Pharmaceutical Manufacturing: Combining Dynamic Modeling and IR Spectroscopy with Changepoint Analysis
Roper, T., Armstrong, C., Miyai, Y., Formosa, A., Rogers, L., Kaushik, P.

09:30 AM

(446g) Heat Transfer Characterization in Flow Reactors for Continuous Pharmaceutical Oxidations
Diop, F. B., Chong, G., Gonzales, E., Teixeira, A. R.

09:48 AM

(446h) Identification of Reaction Pathways Using in-Line Process Analytical Technology (PAT): UV-Vis Spectroscopic Approach
Mohammadparast, F., Addanki Tirumala, R. T., Ramakrishnan, S. B., Andiappan, M.