2021 Annual Meeting

Session: Crystallization Process Development

Chair

Daniel Green, GlaxoSmithKline

Presentations

08:03 AM

(568a) Cephalexin and Amoxicillin Crystal Shape Modification By Manipulating the Supersaturation and Wet Milling
Hossein Salami, Patrick Harris, Andy Bommarius, Martha Grover, Ronald Rousseau

08:24 AM

(568b) Accelerated Early-Stage Enabling API Crystallization Process Development and Scale-up
Ryan Ellis, Moussa Boukerche, Collin Morris, James Stambuli, Michael Lesslie, Jie Chen, Nandkishor Nere

08:45 AM

(568c) Development and Scale-up of a Crystallization Process for a Kinetically-Unfavorable Polymorph
Paul Larsen, Nicole Hough, Christian Lowe, Yamini Krishnan, Patrick McGough, Abraham Schuitman, Joseph Wei, Navraj Hanspal

09:27 AM

(568e) Acid-Catalyzed Esterification Governs the Chain Elongation and the Oriented Attachment in Cof-5 Synthesis
Rajan Bhawnani, Anish Dighe, Santanu Chaudhuri, Meenesh Singh

09:48 AM

(568f) Enabling a Selective Dissolution Scheme for the Removal of Fines in Crystallization with a Hydrocyclone: Modeling and Experimental Validation
Pietro Binel, Marco Mazzotti

10:09 AM

(568g) Crystallization Modeling of a Pharmaceutical Compound for Digital Twin Based in-Silico Optimization with Experimental Validation
Ayse Eren, Botond Szilagyi, Justin Quon, Charles D. Papageorgiou, Zoltan Nagy