2021 Annual Meeting

Session: Continuous Drug Substance – Integrated Processes - Session 2

Chair

Presentations

12:30 PM

(117a) Continuous Manufacturing of Beta-Lactam Antibiotics By Enzymatic Synthesis and Crystallization: A Pilot Plant Study
Hossein Salami, Patrick Harris, Colton Lagerman, Matthew McDonald, Ronald Rousseau, Martha Grover, Andy Bommarius

12:54 PM

(58b) Development of a Stable and Recyclable Biocatalyst for the Reactive Crystallization of Cephalexin Monohydrate
Patrick Harris, Hossein Salami, Martha Grover, Ronald Rousseau, Andy Bommarius

01:18 PM

(117b) Adaptation of a Small-Scale Additive Manufacturing System to Enable End to End Continuous Production of Solid Oral Drug Products
Varun Sundarkumar, Zoltan Nagy, Gintaras Reklaitis

01:42 PM

(117c) Intensified Continuous Purification Platform for Pharmaceutical Systems - Application to the Continuous Manufacturing of Pure Cannabidiol Crystals
Inyoung Hur, Wei-Lee Wu, Ayse Eren, Jaron Mackey, Rojan Pavaresh, Zoltan Nagy

02:06 PM

(117e) Real Time Process Monitoring with PAT for Continuous Pharmaceutical Manufacturing: Toward Advanced Process Control and Real Time Optimization with Ciprofloxacin Synthesis
Yuma Miyai, Anna Forzano, Cameron Armstrong, Luke Rogers, Thomas Roper

02:30 PM

(117f) Dynamic Flowsheet Simulation and Application of Soft Sensors on an Intensified and Integrated Purification Step for Pharmaceutical Upstream Manufacturing
Inyoung Hur, Daniel Casas Orozco, Zoltan Nagy