2021 Annual Meeting

Session: Advances in New Modalities (Large Molecule, Oligos, Peptides, ADCs, Gene therapy, etc.) Product and Process Development (includes invited talks)

Co-Chair

Boung Wook Lee, GlaxoSmithKline

Presentations

03:30 PM

(360a) Analysis of Transformed Bioprocess Data and Application of Hybrid Modeling Approaches to Enhance Upstream Process Development
Kristina Mathis, Boung Wook Lee, Dave Stevenson

03:54 PM

(360b) Challenges in the Pharmaceutical Development of Lipid Nanoparticle Therapeutics
Nelia Viza, Angela Wagner, Yong Liu, Agnes Zhao, Amy Doty, Katelyn Smith, Xiujuan Jia, Jameson Bothe, Yongchao Su, Mingyue Li, Eric Kemp, Adam Socia, Erin Guidry, Marian Gindy

04:42 PM

(360e) Dynamic Optimization of an Ultrafiltration System for the Concentration of Monoclonal Antibody Solutions Under Uncertainty
Francesco Rossi, Jessica Zuponcic, Eduardo Ximenes, Steven Geng, Yinying Tao, Vincent Corvari, Michael Ladisch, Gintaras Reklaitis

05:06 PM

(360f) Confocal Imaging of Protein Gel Layer Formation during Tangential Flow Filtration to Inform Process Conditions Reducing Protein Losses and Increasing Protein Concentration
Jessica Zuponcic, Francesco Rossi, Eduardo Ximenes, Norvin Bruns, Steven Geng, Yinying Tao, Vincent Corvari, Gintaras Reklaitis, Michael Ladisch