2020 Virtual AIChE Annual Meeting

Session: Predictive Scale-Up/Scale-Down for Production of Pharmaceuticals and Biopharmaceuticals I

Chair

Chen, J., Massachusetts Institute of Technology

Co-Chair

Mitchell, N., Process Systems Enterprise

Presentations

08:00 AM

(435a) Reaction Kinetic Model Application to Speed up Development
Ataíde, F., Mateus, E., Volta e Sousa, L., Mourão, M., Ribeiro, A., Odille, F., Assaf, G., Cocchini, U., Lo Brutto, P.

08:15 AM

(435b) Utilizing Mechanistic Modelling to Support Scale-up of Fed-Batch Reaction Process
Bosco, M., Rosa, L., Mitchell, N., Wilkinson, S., Mahadevan, M.

08:30 AM

(435c) Scaling Down a Reactive Crystallization Using Various Mixing Models
Jordan, C., Agustinus, Y., Wilbert, C., Perona, J., Ragazzo, K., Marton, C., Holloway, B.

08:45 AM

(435d) Centrifugation at Scale: Scaling up Based on Bench Top, Pilot Plant and Modeling Data
McKee, L., Riccitelli, M., Carragher, A., Hou, X. S., Chaaya, E.

09:00 AM

(435e) Experimental Confirmation of Scale-Down Mixing Models from Commercial to Lab Scale with CFD for Sterile Drug Products
Flamm, M., Mascaro, T., Quach, A. L., Ikeda, C., Marks, B., Kwofie, F., Schwartz, K.

09:15 AM

(435f) Computational Approaches to Scale-up and Tech-Transfer in Agitated Filter Bed Drying
Sinha, K., Murphy, E., Mummudi Boopathy, M., Bharadwaj, R., Belekar, V. V., Subramaniam, S., Nere, N.