2020 Virtual AIChE Annual Meeting

Session: Particle Formation and Crystallization Processes from Liquids, Slurries, and Emulsions

Chair

Fredrik Nordstrom, Boehringer-Ingelheim

Co-Chair

Presentations

08:00 AM

(601a) Improvement of Drug Substance Bulk Powder Properties through Process Crystallization
Otute Akiti, Kate Donnelly, Niamh McKeever, Lori Jean van Orden

08:15 AM

(601b) Singly?Twinned Growth of Si Crystals upon Chemical Modification
Saman Moniri, Ashwin J. Shahani

08:30 AM

(601c) Elucidating the Influence of Hydroxycitrate on Brushite Crystallization Via Bulk and Interfacial Studies
Ma. Charlene Tapia, Bryan Alamani, Jem Valerie D. Perez, Takeshi Fukuma, Wei Weilin, Kazuki Miyata, Naoyuki Miyashita

08:45 AM

(601d) Islatravir Penultimate Step Crystallization: Purification of an API in the Presence of High Protein Loading from an Enzymatic Cascade
Eric Margelefsky, Sandra A. Robaire, Thomas Kwok, Margaret Miller, Jacob Heltzel, Kevin Sirk, Keith A. Mattern, Jacob H. Forstater, Shane T. Grosser, Whittaker Aaron, Gregory Hughes, Anne Mohan

09:00 AM

(601e) Development of a Crystallization Process for the Final Step of the Biocatalytic Synthesis of Islatravir
Eric Sirota

09:15 AM

(601f) Impact of the Process Conditions of an Evaporation to Dryness Operation Performed in a Conical Screw Vacuum Dryer on the Isolated Product Psd: Lab- and Pilot-Scale Studies
Sélim Douieb, Ugo Cocchini, Benjamin Lorenzini, Georges Assaf

09:30 AM

(601g) A Generalized Approach for Rapid Aqueous MOF Synthesis By Controlling Solution pH
Luke Huelsenbeck, Hongxi Luo, Prince Verma, Jillian Dane, Rachel Ho, Emily Beyer, Hailey Hall, Geoffrey Geise, Gaurav Giri