2020 Virtual AIChE Annual Meeting

Session: Integrated Design for Drug Substance Processes

Chair

Co-Chair

Presentations

08:00 AM

(478b) Data-Driven Process Development and Scale-up of an Acetal Protection Reaction and Crystallization
Karthik Narsimhan, Jonathan P. McMullen, Eric Sirota, Anne Mohan, Joshua Lee

08:15 AM

(478c) Model Development for Enzymatic Reactive Crystallization of ?-Lactam Antibiotics: A Reaction-Diffusion-Crystallization Approach.
Hossein Salami, Matthew McDonald, Andy Bommarius, Colton Lagerman, Martha Grover, Ronald Rousseau, Patrick Harris

08:30 AM

(478e) Optimization of Process Risk, Cost, and Environmental Sustainability during Late Stage Drug Substance Control Strategy Development
Patrick Sipple, Matthew Hickey, Michaël Fenster, Nathaniel D. Kopp, Jose Tabora, Jia Zang, Kenneth Fraunhoffer

08:45 AM

(478f) Digital Design of an Intensified Filtration-Drying Unit for Continuous Manufacturing
Francesco Destro, Inyoung Hur, Zoltan K. Nagy, Daniel Casas Orozco, Massimiliano Barolo, Su-Lin Lee, Mesfin Abdi, Erin Wood, Xin Feng

09:00 AM

(478g) Integrated Filtration and Washing Modelling to Predict Continuous Isolation Performance
Sara Ottoboni, Cameron Brown, Ekaterina Gramadnikova, Jan Sefcik, Chris Price