2020 Virtual AIChE Annual Meeting

Session: Control Strategies in Pharmaceutical Drug Substance and Biologics Development and Manufacturing

Chair

Christopher Marton, Bristol Myers Squibb

Co-Chairs

Joe Hannon, DynoChem Inc
Kevin Seibert, Eli Lilly

Presentations

08:00 AM

(367a) Leveraging of Modeling and Automation in Development of a Control Strategy for a cGMP Buchwald-Hartwig Cross-Coupling
Brandon Reizman, Mark S. Kerr, Mark A. Pietz, Daniel J. Jarmer

08:15 AM

(367c) Moving to a Chromatography-Free Synthesis: Establishing Product-Related and Polymeric Impurity Control Strategy during Process Development
Geoffrey Purdum, Changxia Yuan, Guanghui Zhu, Benjamin M. Cohen, Miao Yu, Qinggang Wang, Amanda Rogers

08:30 AM

(367d) Process Control Strategy Development for an Integrated Continuous Platform for Monoclonal Antibody Manufacturing
Andrew J. Maloney, Dragana Bozinovski, Amos E. Lu, Jose Sangerman, Moo Sun Hong, Anastasia Artamonova, Rui Wen Ou, Weike Sun, Jacqueline Wolfrum, Paul W. Barone, Stacy Springs, Anthony J Sinskey, Elizabeth M. Cummings Bende, Nili Persits, Rajeev J Ram, Richard Braatz

08:45 AM

(367e) Modulating Antibody Glycosylation Using Traditional and PAT Methods
Madiha Khurshid, Prince Bhebe, Li Zhang, Tony Wang, Richard Wu, Jack Chung-Jr Huang

09:00 AM

(367f) Model Predictive in Vitro Dissolution Testing for Real-Time Release in Pharmaceutical End-to-End Integrated Continuous Manufacturing: An Equivalence Study
Qinglin Su, Paul Hermant, Federica Casati, Wei Wu, Atul Dubey, Lucy L. Botros, Stephen Born, Bayan Takizawa, Salvatore Mascia, Bayan Takizawa