2020 Virtual AIChE Annual Meeting

Session: Continuous Processing in Drug Substance Development and Manufacturing

Chair

Dimitrios Gerogiorgis, University of Edinburgh

Co-Chairs

Christopher Marton, Bristol Myers Squibb

Presentations

08:00 AM

(121a) Microfluidics-Based Biocatalyst-Product Separation for Continuous Enzymatic Processes. a Case Study on ?-Lactam Antibiotics Manufacturing
Hossein Salami, Sajad Razavi Bazaz, Matthew McDonald, Martha Grover, Ronald Rousseau, Andy Bommarius, Majid Ebrahimi Warkiani

08:15 AM

(121b) Novel Integration of Continuous Crystallization Platforms for Control of Crystal Size Distribution and Polymorphic Form
Wei-Lee Wu, Shivani Kshirsagar, Joseph Oliva, Christopher L. Burcham, Zoltan K. Nagy

08:30 AM

(121c) A Scalable Membrane Pervaporation Approach for Continuous Flow Ring Closing Metathesis
Matthew Bio, Hannah Murnen, Ning Shangguan, Sudip Majumdar, Christine Parrish, Christopher P. Breen, Timothy Jamison

08:45 AM

(121d) Development of Continuous Homogeneous Hydrogenation Process for Pharmaceuticals Using a Flow Reactor
Onkar Manjrekar, Duygu Gerceker, Greg Storer, Brian Kotecki, Kaid Harper, Elie Chaaya, Shashank Shekhar, Moiz Diwan

09:00 AM

(121e) Liquid Phase Peptide Synthesis Via Nanostar-Sieving
Jet Yeo, Ludmila G. Peeva, Piers Gaffney, Carla Luciani, Fernando Albericio, Andrew G. Livingston

09:15 AM

(121f) Liquid-Liquid Extractions in API Manufacturing Processes: Is Continuous the Way to Go?
Rui Pina Campos, Maria Inês Lopes, Ruth Morais, Susana Nascimento

09:30 AM

(121g) Development and Process Intensification of a Three Step Continuous Flow Process for Telescoped High Energy Reactions
Christopher Lippelt, Pieter Otten, Shawn Conway