From microspheres to tablets, microstructures are at the core of drug performance, formulation design, and process development. In this open discussion workshop, the DigiM team will showcase a suite of high resolution image-based tools for quantifying and correlating microstructures with drug performance and behavior. Novel techniques including AI microstructure quantification, image-based release prediction, and digital drug formulation will be presented. Applications of these techniques for complex dosage forms and solid dosage process development will be discussed.