2020 Virtual AIChE Annual Meeting

(303a) Rational Design of Modified-Release Dosage Forms

Author

Oral modified release (MR) dosage forms are developed by altering the kinetics and/or site of drug release/absorption in order to achieve specific clinical objectives, such as improved patient compliance, optimized efficacy and reduced adverse events. This presentation introduces basic design principles and different MR delivery technologies. It also discusses the importance of understanding material, formulation, process and their interplays in rational product and process development along with case studies.