2019 AIChE Annual Meeting

Session: Protein Engineering

This session focuses on the development of novel methods for engineering proteins for applications in medicine, energy, and bioengineering. Fundamental studies on the structure and structure-function properties of engineered biomolecules are also included.

Chair

Kevin Cash, Colorado School of Mines - CBE

Co-Chair

Jerome M. Fox, University of Colorado, Boulder

Presentations

03:30 PM

(607a) Designing with Nanoscale Building Blocks: Engineering Self-Assembling Protein Superstructures for Applications in Vaccines, Drug Delivery and Biochemical Production
Danielle Tullman-Ercek

04:10 PM

(607b) Developing Formate Dehydrogenase into a Modular Cofactor Regeneration and Sequestration Tool
Nadim Massad, Scott Banta

04:28 PM

(607c) Calamri: Calcium Activated MRI Reporters for Imaging Neuroactivity
Harun Ozbakir, Arnab Mukherjee

04:46 PM

(607d) Rosetta-Inspired Design of Conformationally Constrained Cylic Anti-Amyloid Peptides
Chandler Est, Parth Mangrolia, Regina M. Murphy

05:04 PM

(607e) Understanding the Structural Basis of Protein Activation By Tuning the Pka of an Embedded Charge
Chung-ta Han, Khrysta Pruett, Jichao Song, Song-I Han
(607g) Synthesis and Characterization of a Novel Protac Containing a ?-Hairpin Sequence Motif to Selectively Knockdown Tau Protein
Adam Melvin, Hannah C. Hymel, Jeffery C. Anderson, Jacob H. Pettigrew, Ted J. Gauthier

05:22 PM

(607f) A Coarse-Grained Model to Elucidate the Regulation of Protein Phase Behavior By Post Translational Modifications
Theodora Myrto Perdikari, Gregory L. Dignon, Jeetain Mittal, Nicholas Fawzi